The Effect of Physiotherapy on Dysfunctional Breathing in Children and Adolescents With and Without Asthma

NCT ID: NCT04728191

Last Updated: 2023-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-10

Study Completion Date

2024-12-31

Brief Summary

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The purpose of the study is to investigate the effect of physiotherapeutical instructions on dysfunctional breathing in children and adolescents with or without asthma.

Children and adolescents with dysfunctional breathing, are invited to participate in the intervention study. Participants are stratified by asthma diagnose status and randomized to physiotherapy or standard care. Participants are followed a year after the intervention, to compare the development in asthma control ( if asthma) and quality of life.

Detailed Description

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The purpose of the study is to investigate the effect of physiotherapeutical instructions on dysfunctional breathing in children and adolescents with or without asthma.

All children and adolescents aged 10-17 years, followed in our outpatient clinic with the diagnose of asthma are invited to fulfill the Nijmegen Questionnaire (NQ) and the Asthma Control Questionnaire (ACQ5)

Children and adolescents where asthma was investigated and ruled out are invited to fulfill the NQ.

Data from the electronic patient journal are used as descriptives.

Participants with dysfunctional breathing (NQ \>= 23) are invited to participate in the intervention study. Participants are stratified by asthma diagnose status and randomized to physiotherapy or standard care. Participants are followed a year after the intervention, to compare the development in asthma control measured by ACQ5 (if asthma) and quality of life measured by PedsQL.

The effect of physiotherapy is analyzed separately for participants with and without asthma. In addition, primary outcomes are analyzed in a regression model with asthma status, age and sex as explanatory variables.

Conditions

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Dysfunctional Breathing Asthma in Children Asthma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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+ asthma + intervention

35 participants with asthma aged 10-17 years, randomized to physiotherapy. The intervention consists of 4 instruction lessons spread over 6 weeks. The participants are instructed in a daily ten-minute-program of breathing exercizes.

Group Type EXPERIMENTAL

Physiotherapy

Intervention Type OTHER

physiotherapeutical instructions and training as described.

+ asthma - intervention

35 participants with asthma aged 10-17 years, randomized to standard care. Participants are getting advice about dysfunctional breathing by a physician or nurse in the outpatient clinic.

Group Type ACTIVE_COMPARATOR

standard care

Intervention Type OTHER

Standard care as described.

- asthma + intervention

35 participants without asthma aged 10-17 years, randomized to physiotherapy. The intervention consists of 4 instruction lessons spread over 6 weeks. The participants are instructed in a daily ten-minute-program of breathing exercizes.

Group Type EXPERIMENTAL

Physiotherapy

Intervention Type OTHER

physiotherapeutical instructions and training as described.

- asthma - intervention

35 participants without asthma, which are randomized to standard care. Participants are getting advise about dysfunctional breathing by a physician or nurse in the outpatient clinic.

Group Type ACTIVE_COMPARATOR

standard care

Intervention Type OTHER

Standard care as described.

Interventions

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Physiotherapy

physiotherapeutical instructions and training as described.

Intervention Type OTHER

standard care

Standard care as described.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Asthma group:

* Asthma diagnosed by lung function tests and/or typical symptoms.
* Treatment with inhaled corticosteroids in minimum 3 months.
* ACQ5 \>= 1.5.
* NQ \>= 23.

NonAsthma group

* Asthma denied after lung function tests ( exercise challenge or mannitol challenge)
* NQ \>= 23.

Exclusion Criteria

* Other significant cardiopulmonary or muscoluskeletal conditions.
* Complex functional conditions involving other organ systems.
* patients who already had the physotherapeutical intervention before study start.
Minimum Eligible Age

10 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Odense Patient Data Explorative Network

OTHER

Sponsor Role collaborator

Kolding Sygehus

OTHER

Sponsor Role lead

Responsible Party

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Signe Vahlkvist

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Signe Vahlkvist, PhD

Role: PRINCIPAL_INVESTIGATOR

Kolding Sygehus

Locations

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Signe Vahlkvist

Kolding, , Denmark

Site Status RECRUITING

Countries

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Denmark

Central Contacts

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Signe Vahlkvist, PhD

Role: CONTACT

+45 20 23 14 30

Louise Jürgensen, MD

Role: CONTACT

Facility Contacts

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Signe Vahlkvist, PhD

Role: primary

Louise Jürgensen, MD

Role: backup

Other Identifiers

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S-20200101-b

Identifier Type: -

Identifier Source: org_study_id

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