Dextrose Effect on Postoperative Nausea and Vomiting (PONV)
NCT ID: NCT04726436
Last Updated: 2021-08-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
120 participants
INTERVENTIONAL
2021-01-25
2021-05-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Dextrose 5%
100 mL/ hour of dextrose 5% were given starting 1 hour before operation and continue till approximately middle of surgery by communicating with surgeon to assess the timing and dosing of dextrose solution effect on PONV.
Dextrose 5% in water
One hour before operation, patients were given dexrose 5%100/hour only for 2 hours to end at about middle of surgery
Dextrose 10%
100 mL/ hour of dextrose 10% were given starting 1 hour before operation and continue till approximately middle of surgery by communicating with surgeon
Dextrose 10%
One hour before operation, patients were given dexrose 10 %100/hour only for 2 hours to end at about middle of surgery
Saline placebo
100 mL/ hour of normal saline were given starting 1 hour before operation and continue till approximately middle of surgery by communicating with surgeon
Saline placebo
One hour before operation, patients were given normal saline100/hour only for 2 hours to end at about middle of surgery
Interventions
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Dextrose 5% in water
One hour before operation, patients were given dexrose 5%100/hour only for 2 hours to end at about middle of surgery
Dextrose 10%
One hour before operation, patients were given dexrose 10 %100/hour only for 2 hours to end at about middle of surgery
Saline placebo
One hour before operation, patients were given normal saline100/hour only for 2 hours to end at about middle of surgery
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* ASA I-II who were listed for elective surgery under general anesthesia (surgery which is risk for PONV).
Exclusion Criteria
* Coagulopathy
* Significant hepatic or renal disease
* Diabetes mellitus or abnormal blood glucose on the morning of surgery
* Withdrawal of consent
* Severe intraoperative hypotension requiring large volume intravascular fluid treatment
* Protocol violations including nitrous oxide administration.
18 Years
65 Years
FEMALE
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Omar Makram Soliman
Lecturer of anesthesia and ICU
Locations
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Assiut university hospital
Asyut, Assuit, Egypt
Countries
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References
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Zorrilla-Vaca A, Marmolejo-Posso D, Stone A, Li J, Grant MC. Perioperative Dextrose Infusion and Postoperative Nausea and Vomiting: A Meta-analysis of Randomized Trials. Anesth Analg. 2019 Oct;129(4):943-950. doi: 10.1213/ANE.0000000000004019.
Other Identifiers
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Dextrose PONV
Identifier Type: -
Identifier Source: org_study_id
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