A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients

NCT ID: NCT04716257

Last Updated: 2024-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-14

Study Completion Date

2025-09-14

Brief Summary

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This prospective, multi-center, real-world study is conducted to investigate the impact of different treatment strategies (systemic chemotherapy combined with oophorectomy or with other local treatment or chemotherapy alone) on the prognosis of ovarian metastatic colorectal cancer patients.

Detailed Description

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This study prospectively collects data of patients diagnosed with ovarian metastatic colorectal cancer, meeting inclusion criteria and signing the informed consent. Patients' treatment strategies and survival outcome in the real world will be faithfully recorded.

Conditions

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Ovarian Metastasis Colorectal Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Histologically confirmed colorectal adenocarcinoma;
2. Histologically or radiologically diagnosed with ovarian metastasis, whether or not combined with metastases in other organs;
3. Women ≥18 years of age;
4. Eastern Cooperative Oncology Group performance status score ≤2;
5. Available imaging data if the disease is measurable according to RECIST criteria version 1.1; patients are eligible if there is no measurable lesion.
6. Complete medical records;
7. Informed consent form signed.

Exclusion Criteria

1. Not ovarian metastatic colorectal cancer confirmed by radiology or histology;
2. Drug abuse or other medical, psychological and social disorders that would interfere with cooperation with the requirements of the study;
3. Other conditions that would influence patient compliance;
4. Pregnant or breastfeeding female; male and female unwilling to take any contraceptive measures.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Sun Yat-sen University

OTHER

Sponsor Role collaborator

Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute

UNKNOWN

Sponsor Role collaborator

Changhai Hospital, Naval Medical University

UNKNOWN

Sponsor Role collaborator

West China Hospital

OTHER

Sponsor Role lead

Responsible Party

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Meng Qiu

Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China

Site Status RECRUITING

Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute

Shenyang, Liaoning, China

Site Status RECRUITING

West China Hospital of Sichuan University

Chengdu, Sichuan, China

Site Status RECRUITING

Changhai Hospital, Naval Medical University

Shanghai, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Meng Qiu, M.D.

Role: CONTACT

+86-28-85422589

Facility Contacts

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Peirong Ding, Ph.D.

Role: primary

020-87343533

Rui Zhang, Ph.D.

Role: primary

024-31916293

Meng Qiu, M.D.

Role: primary

+86-28-85422589

Wei Zhang, Ph.D.

Role: primary

021-31166666

Other Identifiers

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20201296

Identifier Type: -

Identifier Source: org_study_id

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