Perceived Alcohol Rewards and Risks Study

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-11-13

Study Completion Date

2017-04-05

Brief Summary

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The identification of mechanisms that underlie how people reduce or eliminate alcohol use is a critical public health issue. Understanding these mechanisms can inform how to effectively intervene with problem drinkers. Thus far it has been a challenge for the alcohol research field to find consistent empirical evidence in support of candidate mechanisms of behavior change. Scientific advancement in this area may be aided by longitudinal transdisciplinary research on the interplay between behavioral intervention, cognition, and brain activity to understand underlying processes of behavior change among heavy drinkers. This study employed a randomized 2-arm repeated measures design with a sample of non-treatment seeking adult heavy drinkers to examine changes in perceived reward value and risks of alcohol use as a mechanism of alcohol behavior change after a brief behavioral intervention. Participants were randomized to either a 1-session behavioral intervention or to an attention-matched control condition and immediately after completed an fMRI scan. The focus of this project is to examine if group differences in perceived alcohol reward value after the intervention mediates an intervention effect on reducing alcohol use in the 1 month following the intervention.

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Detailed Description

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Conditions

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Heavy Drinking

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Brief Alcohol Intervention

A brief intervention consisting of a 30-45 minute individual face-to-face session based on the principles of motivational interviewing.

Group Type ACTIVE_COMPARATOR

Brief Alcohol Intervention

Intervention Type BEHAVIORAL

Brief alcohol intervention uses a motivational interviewing approach and covers the following components: giving information about the possible health risks associated with alcohol use, placing the responsibility for change on the individual, discussing the reasons for drinking and downsides of drinking, and setting a goal and change plan if the participant is receptive.

Attention-Matched Control Condition

Brief attention-matched control condition.

Group Type SHAM_COMPARATOR

Control Condition

Intervention Type BEHAVIORAL

The attention-matched control condition consisting of a 30-min video about astronomy.

Interventions

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Brief Alcohol Intervention

Brief alcohol intervention uses a motivational interviewing approach and covers the following components: giving information about the possible health risks associated with alcohol use, placing the responsibility for change on the individual, discussing the reasons for drinking and downsides of drinking, and setting a goal and change plan if the participant is receptive.

Intervention Type BEHAVIORAL

Control Condition

The attention-matched control condition consisting of a 30-min video about astronomy.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. engaged in regular heavy drinking, as indicated by consuming 5 or more drinks per occasion for men or 4 or more drinks per occasion for women at least 4 times in the month prior to enrollment
2. a score of ≥ 8 on the Alcohol Use Disorder Identification Test (AUDIT)

Exclusion Criteria

1. under the age of 21
2. currently receiving treatment for alcohol problems, history of treatment in the 30 days before enrollment, or currently seeking treatment
3. a positive urine toxicology screen for any drug other than cannabis
4. a lifetime history of schizophrenia, bipolar disorder, or other psychotic disorder
5. serious alcohol withdrawal symptoms
6. history of epilepsy, seizures, or severe head trauma
7. non-removable ferromagnetic objects in body
8. claustrophobia
9. pregnancy

Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No