Eye Movements Recording Using a Smartphone: Comparison to Standard Video-oculography in Patients With Multiple Sclerosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-10-08

Study Completion Date

2021-10-30

Brief Summary

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This study aims to compare measurements obtained through the e-VOG application (mobile application, usable on mobile phones or tablets, to measure eye movements) with measurements from the standard video-oculography device (Eye-Tracker®T2), in patient with Multiple Sclerosis.

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Detailed Description

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Based on literature, investigators hypothesize that it would be relevant to focus more broadly on subclinical abnormalities of oculomotricity in multiple sclerosis (MS). However, the difficulty of accessing video-oculography platforms (or eye-tracking devices) is probably one of the main limitations to performing this type of assessment.

To respond this problem, the "Resources and Skills Center-Multiple Sclerosis" (CRC SEP) team at the Nice University Hospital Center (France) has developed a mobile application (named e-VOG), usable on mobile phones or tablets, to measure eye movements. e-VOG reproduces the classic paradigms of video-oculography to collect data similar to standard video-oculography recording (saccade latency and speed, anti-saccade error rate, presence of fixation abnormalities).

e-VOG will not replace standard video-oculography platforms, because its technical characteristics are not as high. But investigators hypothesize that this application could constitute a screening tool for subclinical oculomotor abnormalities, usable by neurologists in consultation, directly on their mobile, which would make it possible to select a smaller population of patients in whom a further exploration by standard video-oculography would be indicated.

Memory Center of the Rainier III Gerontologic Center (Princess Grace Hospital - Monaco) is equipped with a standard video-oculography device, also named eye-tracking device (Eye-Tracker®T2), which records eye movements at a high frequency and measures saccades parameters (latency, speed, amplitudes etc...).

This study is a collaborative study between the Center Rainier III team and the CRC SEP team in Nice. Its objective will be to compare measurements obtained through the e-VOG application with measurements from the standard video-oculography device.

Conditions

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Multiple Sclerosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Multiple Sclerosis (Eye-Tracker®T2 + e-VOG)

Multiple Sclerosis subjects who first perform standard video-oculography assessment, followed by e-VOG digital assessment.

Eye-Tracker®T2 + e-VOG

Intervention Type OTHER

* 1st step: eyes movements assessed with standard video-oculography device
* 2° step: eyes movements assessed with e-VOG digital application
* Patient study duration is about 30 minutes, the day the patient performs their standard video-oculography examination in routine care

Multiple Sclerosis (e-VOG + Eye-Tracker®T2)

Multiple Sclerosis subjects who first perform e-VOG digital assessment, followed by the standard video-oculography assessment.

e-VOG + Eye-Tracker®T2

Intervention Type OTHER

* 1st step: eyes movements assessed with e-VOG digital application
* 2° step: eyes movements assessed with standard video-oculography device
* Patient study duration is about 30 minutes, the day the patient performs their standard video-oculography examination in routine care

Interventions

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Eye-Tracker®T2 + e-VOG

* 1st step: eyes movements assessed with standard video-oculography device
* 2° step: eyes movements assessed with e-VOG digital application
* Patient study duration is about 30 minutes, the day the patient performs their standard video-oculography examination in routine care

Intervention Type OTHER

e-VOG + Eye-Tracker®T2

* 1st step: eyes movements assessed with e-VOG digital application
* 2° step: eyes movements assessed with standard video-oculography device
* Patient study duration is about 30 minutes, the day the patient performs their standard video-oculography examination in routine care

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male or Female.
* 18 years old and above.
* referred by a neurologist to perform a video-oculography (Eye-Tracking) examination as part of routine care.
* with Multiple Sclerosis (defined according to McDonald's 2017 criteria).
* covered by a health insurance system
* volunteer, able to give free, informed and written consent.

Exclusion Criteria

* General anaesthesia within 3 months.
* Neurological, ophthalmological or general pathology preventing the realization of a video-oculography examination.
* Oculomotor abnormality detectable on clinical examination by the neurologist prescribing the standard video-oculography examination.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No