Adolescent Idiopathic Scoliosis and Proprioceptive Defect

NCT ID: NCT04682379

Last Updated: 2024-04-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

166 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-11

Study Completion Date

2024-12-31

Brief Summary

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This is the first clinical study to examine the spinal and peripheral proprioceptive deficits in longitudinal terms among subjects with adolescent idiopathic scoliosis.

Detailed Description

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Conditions

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Adolescent Idiopathic Scoliosis Idiopathic Scoliosis Scoliosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Scoliotic patients with proprioceptive deficits

Study subjects possessed statistically significant differences in testing outcomes of proprioception compared with healthy controls.

Proprioceptive assessment

Intervention Type DIAGNOSTIC_TEST

1. Trunk flexion-extension repositioning test
2. Trunk lateral-flexion repositioning test
3. Trunk axial-rotation repositioning test
4. Neck rotation repositioning test
5. Elbow flexion repositioning test
6. Knee extension repositioning test

Scoliotic patients without proprioceptive deficits

Study subjects with similar testing results of proprioception compared with healthy controls.

Proprioceptive assessment

Intervention Type DIAGNOSTIC_TEST

1. Trunk flexion-extension repositioning test
2. Trunk lateral-flexion repositioning test
3. Trunk axial-rotation repositioning test
4. Neck rotation repositioning test
5. Elbow flexion repositioning test
6. Knee extension repositioning test

Interventions

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Proprioceptive assessment

1. Trunk flexion-extension repositioning test
2. Trunk lateral-flexion repositioning test
3. Trunk axial-rotation repositioning test
4. Neck rotation repositioning test
5. Elbow flexion repositioning test
6. Knee extension repositioning test

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* diagnosis of adolescent idiopathic scoliosis
* did not receive or failed conservative treatment

Exclusion Criteria

* spinal injury, fracture, or spinal tumour
* neurological deficit
* brain or spinal cord abnormality
* developmental delay
* psychological disorder
Minimum Eligible Age

10 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kenneth Cheung

Role: PRINCIPAL_INVESTIGATOR

The University of Hong Kong

Locations

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The Duchess of Kent Children's Hospital

Hong Kong, , Hong Kong

Site Status

Countries

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Hong Kong

References

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Lau KKL, Law KKP, Kwan KYH, Cheung JPY, Cheung KMC, Wong AYL. Timely Revisit of Proprioceptive Deficits in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-Analysis. Global Spine J. 2022 Oct;12(8):1852-1861. doi: 10.1177/21925682211066824. Epub 2021 Dec 15.

Reference Type BACKGROUND
PMID: 34911378 (View on PubMed)

Lau KKL, Law KKP, Kwan KYH, Cheung JPY, Cheung KMC. Proprioception-related gene mutations in relation to the aetiopathogenesis of idiopathic scoliosis: A scoping review. J Orthop Res. 2023 Dec;41(12):2694-2702. doi: 10.1002/jor.25626. Epub 2023 Jun 4.

Reference Type BACKGROUND
PMID: 37203456 (View on PubMed)

Lau KK, Kwan KY, Cheung JP, Chow W, Law KK, Wong AY, Chow DH, Cheung KM. Reliability of a three-dimensional spinal proprioception assessment for patients with adolescent idiopathic scoliosis. Eur Spine J. 2022 Nov;31(11):3013-3019. doi: 10.1007/s00586-022-07338-0. Epub 2022 Aug 3.

Reference Type BACKGROUND
PMID: 35922635 (View on PubMed)

Other Identifiers

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UW 20-525

Identifier Type: -

Identifier Source: org_study_id

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