Assessing the Technique of Ovarian Tissue Cryopreservation by Vitrification in Vietnam
NCT ID: NCT04666376
Last Updated: 2020-12-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
43 participants
INTERVENTIONAL
2021-01-01
2022-01-31
Brief Summary
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Detailed Description
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Cortex fragments of each group will have:
* Follicle survival evaluation by Neutral red staining
* Histological evaluation by Hematoxylin and Eosin staining
* Evaluation relative Growth Differentiation Factor 9 (GDF-9) and Caspase-3 gene expression by real-time Polymerase chain reaction (PCR).
Comparison of data collected from 2 groups will be carried on to evaluate the effectiveness of the technique before applying this technique for cancer patients in Vietnam.
Conditions
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Study Design
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NA
SINGLE_GROUP
OTHER
NONE
Study Groups
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Vitrified ovarian tissue
Ovarian tissue will be vitrified and warmed by Ova kit type M protocol.
evaluation of the effectiveness of vitrification technique on ovarian tissue quality
there are 3 types of experiments in each group, including Follicle survival evaluation by Neutral red staining, Histological evaluation by Hematoxylin and Eosin staining, 2.4. Evaluation GDF-9 and Caspase-3 gene expression by real-time PCR.
Interventions
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evaluation of the effectiveness of vitrification technique on ovarian tissue quality
there are 3 types of experiments in each group, including Follicle survival evaluation by Neutral red staining, Histological evaluation by Hematoxylin and Eosin staining, 2.4. Evaluation GDF-9 and Caspase-3 gene expression by real-time PCR.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
45 Years
FEMALE
No
Sponsors
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Mỹ Đức Hospital
OTHER
Responsible Party
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Principal Investigators
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Tuong M Ho, MD, MCE
Role: PRINCIPAL_INVESTIGATOR
Hope Research Center
Locations
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My Duc Hospital
Ho Chi Minh City, , Vietnam
Countries
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Central Contacts
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Facility Contacts
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Lan Nguyen, MSC
Role: primary
Vinh Dang, MD,MCE
Role: backup
Other Identifiers
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15/20/DD-BVMD
Identifier Type: -
Identifier Source: org_study_id