Vitrification for Ovarian Tissue Harvesting

NCT ID: NCT03649087

Last Updated: 2018-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-01

Study Completion Date

2018-12-01

Brief Summary

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Increasing interest has emerged concerning ovarian tissue cryopreservation and subsequent transplantation as a potential way of preserving fertility in cancer patients as well as for women who just wish to delay childbearing. As the majority of existing protocols use the slow freezing method, this study aims to test vitrification techniques of ovarian cortex.

Detailed Description

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Conditions

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Ovary; Anomaly

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Vitrification of ovarian tissue
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Interventions

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Vitrification

Vitrification of ovarian tissue

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* female-to-male transsexuals
* gender completing operation
* signed informed consent form
* willingness to donate ovarian tissue for research purposes
* age \>=18 years

Exclusion Criteria

* malignant disease
* age under 18 years
* refusal to donate ovarian tissue
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Maximilian Franz, M.D.

OTHER

Sponsor Role lead

Responsible Party

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Maximilian Franz, M.D.

MD

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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University Clinic of Obstetrics and Gynaecology of the Medical University of Vienna

Vienna, , Austria

Site Status RECRUITING

Countries

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Austria

Central Contacts

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Julian Marschalek, MD

Role: CONTACT

0043140400 ext. 28970

Detlef Pietrowski, Dr.

Role: CONTACT

0043140400 ext. 28970

Facility Contacts

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Julian Marschalek, MD

Role: primary

0043140400 ext. 28970

Detlef Pietrowski, Dr.

Role: backup

0043140400 ext. 28970

References

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Marschalek J, Egarter C, Nouri K, Dekan S, Ott J, Frank M, Pietrowski D. The effect of different vitrification protocols on cell survival in human ovarian tissue: a pilot study. J Ovarian Res. 2021 Dec 6;14(1):170. doi: 10.1186/s13048-021-00924-8.

Reference Type DERIVED
PMID: 34872604 (View on PubMed)

Marschalek J, Pietrowski D, Dekan S, Marschalek ML, Brandstetter M, Ott J. Markers of vitality in ovaries of transmen after long-term androgen treatment: a prospective cohort study. Mol Med. 2020 Sep 5;26(1):83. doi: 10.1186/s10020-020-00214-x.

Reference Type DERIVED
PMID: 32891132 (View on PubMed)

Other Identifiers

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2204

Identifier Type: -

Identifier Source: org_study_id

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