MSCs Therapy for Cerebral Palsy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-12-02

Study Completion Date

2022-12-01

Brief Summary

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Cerebral palsy (CP) is the most common physical disability in childhood. CP comprises a heterogeneous group of disorders that are the result of a non-progressive disruption or injury that occurred during fetal brain development or within the first two years of life.

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Detailed Description

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This disruption can result in spasticity, dystonia, muscle contractures, weakness and difficulty in coordination that ultimately affects the ability to control movements. Resultant activity limitations may affect gross motor movements, fine motor movements, speech and communication, as well as eating and drinking.

Conditions

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Stem Cell Transplant Complications

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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stem cells

Intravenous and Intrathecal transplantation of specific populations of purified bone marrow-derived stem cells and mesenchymal stem cells.

Group Type EXPERIMENTAL

stem cells

Intervention Type OTHER

Intravenous and Intrathecal transplantation of specific populations of purified bone marrow-derived stem cells and mesenchymal stem cells.

Interventions

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stem cells

Intravenous and Intrathecal transplantation of specific populations of purified bone marrow-derived stem cells and mesenchymal stem cells.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* • Must be more than 2 year of age and less than 12 years of age at the time of screening for inclusion in the study.

* Clinical evidence of a non-progressive motor disability due to brain dysfunction.

Exclusion Criteria

* • Intractable seizures

* Traumatic brain injury
* Genetic disorder
* Current Infection
* Renal insufficiency
* Hepatic disease
* HIV+ (as demonstrated by positive blood test)
* Immunosuppression

Minimum Eligible Age

2 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No