A Comparison of Conventional Physical Therapy, Powered Exoskeleton, and Hybrid Physical Therapy With Exoskeleton

NCT ID: NCT04648878

Last Updated: 2025-03-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

6 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-14

Study Completion Date

2024-12-18

Brief Summary

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The purpose of this investigator-initiated study is to establish if powered exoskeleton therapy as a part of a rehabilitation program can be used as a standard of care in stroke rehabilitation.

Detailed Description

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This prospective randomized control trial with three treatment arms will begin by:

* Determining if the subject is a candidate for exoskeleton treatment.
* Randomly assigning subjects to three groups (physical therapy only, exoskeleton only, or a hybrid of physical therapy and exoskeleton).
* Body measurements to individualize the fit of the exoskeleton to each subject at each session.
* Activities-based balance confidence (ABC) questionnaire will be administered before and after the study begins.
* Timed up and go test (TUGT).
* Ten-meter walk test (10MWT).
* Six-minute walk test (6MWT)
* Berg Balance Test (BBT).
* Five times sit to stand (5XSTS).
* Heart rate through a portable heartrate monitor.

Conditions

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Stroke

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Caregivers
participants will be instructed to not reveal which treatment arm they have been assigned to

Study Groups

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Group A - Hybrid combination

Group A (n=12) will receive 18 alternating visits of conventional physical therapy and powered exoskeleton gait training with a wearable robotic powered exoskeleton , three times a week for approximately 6 weeks.

Group Type EXPERIMENTAL

Hybrid combination of physical therapy and powered exoskeleton

Intervention Type OTHER

18 alternating visits of conventional physical therapy and powered exoskeleton gait training with a wearable robotic powered exoskeleton , three times a week for approximately 6 weeks

Group B - Powered Exoskeleton only

Group B (n=12) will receive 18 visits of powered exoskeleton only, three times a week for approximately 6 weeks.

Group Type EXPERIMENTAL

Powered Exoskeleton Only

Intervention Type OTHER

18 visits of powered exoskelton only, three times a week for approximately 6 weeks

Group C - Physical Therapy only

Group C (n=12) will receive 18 visits of physical therapy, three times a week for approximately 6 weeks. Upon completion of the data collection portion of the study, group C will receive 9 sessions, three times a week for approximately three weeks of powered exoskeleton therapy. Data will not be collected or reported during this phase, but but may be retained for future approved use.

Group Type EXPERIMENTAL

Physical Therapy only

Intervention Type OTHER

18 visits of physical therapy only, three times a week for approximately 6 weeks

Interventions

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Hybrid combination of physical therapy and powered exoskeleton

18 alternating visits of conventional physical therapy and powered exoskeleton gait training with a wearable robotic powered exoskeleton , three times a week for approximately 6 weeks

Intervention Type OTHER

Powered Exoskeleton Only

18 visits of powered exoskelton only, three times a week for approximately 6 weeks

Intervention Type OTHER

Physical Therapy only

18 visits of physical therapy only, three times a week for approximately 6 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Males and Females 18 years of age or older post-stroke

* 3 Ashworth score are involved in a standing program less than 220 lbs 5'0" through 6'4" have the ability to follow one-step commands near normal range-of-motion for the knees, hips, and ankles
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Loma Linda University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michael Davidson, MSE MPH

Role: PRINCIPAL_INVESTIGATOR

Loma Linda University O&P

Locations

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Loma Linda University

Loma Linda, California, United States

Site Status

Countries

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United States

Other Identifiers

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5190407

Identifier Type: -

Identifier Source: org_study_id

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