Moving Together: An Online Group Movement Program for People Living With Memory Loss and Caregivers

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

224 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-18

Study Completion Date

2023-05-12

Brief Summary

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To determine whether Moving Together improves quality of life in people with memory loss (PWML) and caregivers (CG) by performing a randomized, controlled trial (RCT) with a waitlist control group in 224 dyads.

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Detailed Description

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The investigators will perform an RCT with a 12-week delayed start control group in 224 dyads of PWMLs and CGs. The primary outcome in PWML will be self-rated quality of life (Quality of Life in Alzheimer's Disease, QOL-AD). Secondary outcomes will include: a) self-reported emotional well-being; b) self-reported social isolation; c) self-reported mobility; and d) directly assess cognitive performance. In CGs, the primary outcome will be self-rated quality of life (SF-12). Secondary outcomes in CGs will include: a) healthy days; b) self-efficacy; c) burden; d) social isolation; e) ability to self-regulate; f) positive affect; and g) sleep quality. In addition, the investigators will ask CGs to report sleep quality, mobility, and cognitive function for PWML. Additional exploratory outcomes will include health services utilization (hospitalizations, emergency department visits) and falls.

In addition to the RCT, the investigators propose to compare health utilization outcomes in study participants to a matched 'no contact' comparison sample of patients with dementia diagnoses who receive care in the University of California San Francisco (UCSF) Health system.

Conditions

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Alzheimer Disease Dementia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

Delayed-start control group

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Dyads will be enrolled and randomized in blocks of 16 (n=8 immediate start, n=8 waitlist). The randomization sequence will be generated in advance by Dr. Barnes' team using a random number generator and will be maintained in a secure location. Individuals who collect or analyze outcome data will be unaware of the randomization sequence and blinded to group assignment.

Study Groups

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Immediate Start

The Immediate Start group will participate in the 12-week Moving Together program after completing the baseline assessment. Moving Together is a gentle, live-streaming, group movement program designed specifically for people with memory loss (PWML) and caregivers (CG) to do together. It is based on the in-person Preventing Loss of Independence through Exercise (PLIÉ) and Paired PLIÉ programs. The program combines physical movements to help maintain daily function with mindful body awareness exercises and social interactions to provide a comprehensive, multi-domain program.

Group Type EXPERIMENTAL

Moving Together

Intervention Type BEHAVIORAL

Two-way livestreaming virtual group classes will be offered for 1 hour, 2 days/week for 12 weeks to all participants. Classes will be led by a trained instructor who will demonstrate all movements and will provide brief explanations for the goals of movements. Consistent with the in-person program, classes will focus on the 7 guiding principles of Moving Together:

1. repetition with variation (to promote procedural learning);
2. progressive, functional movements (to improve daily function);
3. slow pace and step-by-step instruction (to minimize cognitive demands);
4. participant-centered goal orientation (to enhance personal meaningfulness of movements);
5. body awareness, mindfulness and breathing (to encourage present-centeredness);
6. social interaction (to promote meaningful connection); and
7. positive emotions (to promote feelings of well-being.

Delayed Start

A Delayed Start group will be encouraged to continue with their usual daily activities during the first 12 weeks of the study and will begin the Moving Together program after completing the mid-point assessment.

Group Type EXPERIMENTAL

Moving Together

Intervention Type BEHAVIORAL

Two-way livestreaming virtual group classes will be offered for 1 hour, 2 days/week for 12 weeks to all participants. Classes will be led by a trained instructor who will demonstrate all movements and will provide brief explanations for the goals of movements. Consistent with the in-person program, classes will focus on the 7 guiding principles of Moving Together:

1. repetition with variation (to promote procedural learning);
2. progressive, functional movements (to improve daily function);
3. slow pace and step-by-step instruction (to minimize cognitive demands);
4. participant-centered goal orientation (to enhance personal meaningfulness of movements);
5. body awareness, mindfulness and breathing (to encourage present-centeredness);
6. social interaction (to promote meaningful connection); and
7. positive emotions (to promote feelings of well-being.

Interventions

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Moving Together

Two-way livestreaming virtual group classes will be offered for 1 hour, 2 days/week for 12 weeks to all participants. Classes will be led by a trained instructor who will demonstrate all movements and will provide brief explanations for the goals of movements. Consistent with the in-person program, classes will focus on the 7 guiding principles of Moving Together:

1. repetition with variation (to promote procedural learning);
2. progressive, functional movements (to improve daily function);
3. slow pace and step-by-step instruction (to minimize cognitive demands);
4. participant-centered goal orientation (to enhance personal meaningfulness of movements);
5. body awareness, mindfulness and breathing (to encourage present-centeredness);
6. social interaction (to promote meaningful connection); and
7. positive emotions (to promote feelings of well-being.

Intervention Type BEHAVIORAL

Other Intervention Names

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Together Senior Health

Eligibility Criteria

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Inclusion Criteria

* People with memory loss (PWML):

* U.S. resident;
* English language fluency;
* diagnosis of Alzheimer's disease or other dementia; mild severity, assessed using the Quick Dementia Rating System.
* Caregivers (CG):

* U.S. resident;
* English language fluency;
* Primary caregiver for PWML;
* own one or more devices that can be used to participate in two-way livestreaming video classes (e.g., smart phone/tablet + TV, laptop or desktop with webcam, smart TV);
* willing and able to participate in two-way livestreaming group movement classes with person with PWML.

Exclusion Criteria

* Age \< 18 years;
* primarily use wheelchair inside home;
* limited life expectancy (e.g., enrolled in hospice, meta-static cancer);
* physical limitations that could affect ability to participate (e.g., difficulty sitting for 1 hour, chronic pain, vertigo);
* severe visual impairment (e.g., unable to observe instructor's movements on screen);
* severe hearing impairment (e.g., unable to hear instructor's requests);
* behavioral or psychiatric issues that could be disruptive in group setting (e.g., history of physical or verbal abuse, schizophrenia, bipolar disorder, substance abuse);
* unable to provide consent/assent;
* planning to travel for \>1 week during initial 12-week study period.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No