ICNBs for Post-op Pain in Breast Surgery

NCT ID: NCT04606836

Last Updated: 2020-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-12-07

Study Completion Date

2021-08-31

Brief Summary

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The authors will conduct this study to analyze the effectiveness of peri-operative intercostal nerve blocks (ICNBs) in reducing acute postoperative pain after reconstructive breast surgery and mammoplasty and how it affects the length of hospital stay.

Detailed Description

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Conditions

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Pain, Postoperative Length of Stay

Keywords

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ICNB pain

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Cases will be recruited prospectively and controls will be taken retrospectively
Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors
The statistician will be masked to the groups the participants fall in (case vs control).

Study Groups

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Prospective Cases

These cases will be recruited prospectively, and receive the intercostal nerve block(s) on operated site(s). Peri-operative injections of 30 ml of 0.25% Bupivacaine each, injected over the 4th, 5th, and 6th ribs on the operated site(s).

Group Type EXPERIMENTAL

Bupivacaine Hydrochloride

Intervention Type DRUG

See group descriptions

Retrospective Controls

Controls will be gathered retrospectively from chart reviews where patient did not receive a intercostal nerve blocker bilaterally.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Bupivacaine Hydrochloride

See group descriptions

Intervention Type DRUG

Other Intervention Names

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Marcaine

Eligibility Criteria

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Inclusion Criteria

* American Society of Anesthesiologists Classification (ASA Class) 3 and below.
* Bilateral or unilateral breast surgery including cancer extirpation, reconstruction (implant and expander), oncoplastic surgery (\<200 gm), breast augmentation and breast reduction, etc.

Exclusion Criteria

* Patients who refuse local anesthesia.
* Patients who cannot receive local anesthesia.
* Below the age of 20 and above the age of 70.
* Patients requiring reoperation due to complications of mammoplasty or another breast surgery.
* Poorly controlled diabetics, uncontrolled hypertension, heart disease, arrhythmias, diagnosed with bipolar and generalized anxiety disorders.
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Jewish Hospital and St. Mary's Healthcare

OTHER

Sponsor Role collaborator

Baptist Health

UNKNOWN

Sponsor Role collaborator

Kleinert, Kutz and Associates

OTHER

Sponsor Role collaborator

Christine M. Kleinert Institute for Hand and Microsurgery

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michelle Palazzo, MD

Role: PRINCIPAL_INVESTIGATOR

Christine M. Kleinert Institute for Hand and Microsurgery

Locations

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Ambulatory Surgery Center, Kleinert Kutz Hand Care Center

New Albany, Indiana, United States

Site Status RECRUITING

Baptist Health Floyd

New Albany, Indiana, United States

Site Status RECRUITING

Christine M Kleinert Institute for Hand and Microsurgery

Louisville, Kentucky, United States

Site Status RECRUITING

HCCOC, Jewish Hospital

Louisville, Kentucky, United States

Site Status RECRUITING

Baptist Health Louisville

Louisville, Kentucky, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Julianne Sutton, MPH

Role: CONTACT

Phone: 5025620390

Email: [email protected]

Facility Contacts

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Michelle Palazzo, MD

Role: primary

Michelle Palazzo, MD

Role: primary

Michelle Palazzo, MD

Role: primary

Julianne Sutton, MPH

Role: backup

Michelle Palazzo, MD

Role: primary

Michelle Palazzo, MD

Role: primary

References

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Park JW, Kim JH, Woo KJ. Intraoperative Intercostal Nerve Block for Postoperative Pain Control in Pre-Pectoral versus Subpectoral Direct-to-Implant Breast Reconstruction: A Retrospective Study. Medicina (Kaunas). 2020 Jun 30;56(7):325. doi: 10.3390/medicina56070325.

Reference Type RESULT
PMID: 32629834 (View on PubMed)

Other Identifiers

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20.0781

Identifier Type: -

Identifier Source: org_study_id