Feasibility Study Evaluating the Efficacy of a Wireless Vital Signs Monitor for Critically Ill Newborns in Kenya

NCT ID: NCT04606589

Last Updated: 2023-03-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

167 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-01

Study Completion Date

2021-05-30

Brief Summary

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The neoGuard device is a 4-in-1 wearable vital signs monitor designed to continuously measure temperature, pulse rate (PR), respiratory rate (RR) and blood oxygen saturation (SpO2) in newborns. In this study, researchers will evaluate the feasibility of the neoGuard device at two rural health facilities in Western Kenya and assess the preliminary efficacy of the technology in improving health outcomes for newborns.

This is a pre/post intervention study. The standard-of-care arm (n=223) will be enrolled between 20 Oct - 20 Nov, 2020 and the neoGuard intervention arm (n=223) will be enrolled between 1 - 31 Dec, 2020.

Detailed Description

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Conditions

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Newborn Morbidity Newborn Complication

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

This is a simple pre/post interventional study model.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Standard-of-care

The standard-of-care arm will receive intermittent monitoring of pulse rate and blood oxygen saturation with a conventional pulse oximeter. Temperature and respiratory rate will also be monitored intermittently with a digital thermometer and manual counting of breaths respectively.

Group Type NO_INTERVENTION

No interventions assigned to this group

neoGuard vital signs monitor

The intervention group will receive continuous vital signs monitoring of pulse rate, blood oxygen saturation, temperature and respiratory rate with the neoGuard device.

Group Type EXPERIMENTAL

neoGuard vital signs monitor

Intervention Type DEVICE

The neoGuardTM device is a 4-in-1 wearable vital signs monitor designed to continuously measure temperature, pulse rate, respiratory rate and blood oxygen saturation in newborns.

Interventions

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neoGuard vital signs monitor

The neoGuardTM device is a 4-in-1 wearable vital signs monitor designed to continuously measure temperature, pulse rate, respiratory rate and blood oxygen saturation in newborns.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age \<28 days
* Admitted to the neonatal intensive care unit
* Weight at birth/admission ≥2000 g
* Low-to-moderate disease severity as determined by the Signs of Inflammation in Children that Kill (SICK) score card (SICK score ≤2.4 at admission is eligible)
* Parent/guardian willing to provide informed consent for their newborn to participate in study

Exclusion Criteria

* Age \>28 days
* Has a condition that impairs them from wearing the device, such as hydrocephaly.
* Weight at birth \<2000 g
* Very severe disease status (SICK score \>2.4 at admission)
Minimum Eligible Age

1 Day

Maximum Eligible Age

28 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Center for Public Health and Development

UNKNOWN

Sponsor Role collaborator

Neopenda, PBC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bernard Olayo, MD

Role: PRINCIPAL_INVESTIGATOR

Center for Public Health and Development

Locations

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Kakamega County Referral Hospital

Kakamega, , Kenya

Site Status

Countries

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Kenya

Other Identifiers

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MSU/DRPI/MUERC/00864/20

Identifier Type: -

Identifier Source: org_study_id

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