Specific Methylation Profiles in HNSCC

NCT ID: NCT04567056

Last Updated: 2025-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-16

Study Completion Date

2026-06-01

Brief Summary

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In the study, N-20190047, the investigators aim to define specific methylation patterns in a group of patients with head and neck squamous cell carcinomas.

With this study the investigators aim to validate these findings in a larger cohort.

Detailed Description

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Conditions

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Head and Neck Squamous Cell Carcinoma

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Cancer group

Patients with verified head and neck squamous cell carcinomas

Blood sample

Intervention Type DIAGNOSTIC_TEST

A separate blood sample will be taken for methylation-analyses

Control group

Matched control group without active or earlier cancer and a normal ENT examination.

Blood sample

Intervention Type DIAGNOSTIC_TEST

A separate blood sample will be taken for methylation-analyses

Interventions

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Blood sample

A separate blood sample will be taken for methylation-analyses

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Written informed consent
* Verified head and neck squamous cell carcinoma


* Written informed consent
* Normal ENT-examination

Exclusion Criteria

* Other active cancer
* Uncontrolled comorbidity
* Unable to give informed consent

Control group:


* Other active cancer
* Uncontrolled comorbidity
* Unable to give informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Aalborg University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Christian Sander Danstrup

Associate Professor, M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Michael Gaihede, Professor

Role: PRINCIPAL_INVESTIGATOR

Department of Otolaryngology - Head and Neck Surgery, Aalborg University Hospital

Locations

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Department of Otolaryngology - Head and Neck Surgery

Aalborg, , Denmark

Site Status RECRUITING

Countries

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Denmark

Central Contacts

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Christian Danstrup, M.D.

Role: CONTACT

+45 23800598

Michael Gaihede, Professor

Role: CONTACT

Facility Contacts

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Christian Danstrup, M.D

Role: primary

+45 23800598

Other Identifiers

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N-20190047-2

Identifier Type: -

Identifier Source: org_study_id

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