Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS Patients

NCT ID: NCT04550650

Last Updated: 2022-04-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

4 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-04-06

Study Completion Date

2020-09-01

Brief Summary

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Different therapies can improve clinical and motor symptoms of multiple sclerosis (MS) similarly, but studies comparing the effects of different exercise therapies on clinical and motor outcomes are scant. We compared the effects of exergaming (EXE), balance (BAL), cycling (CYC), proprioceptive neuromuscular facilitation (PNF), and a standard care wait-listed control group (CON) on clinical and motor symptoms and quality of life (QoL) in people with MS (PwMS).

Methods: PwMS (n = 68, 90% female; age, 47.0 yr; Expanded Disability Status Scale score 5-6) were randomized into five groups. Before and after the interventions (five times a week for 5 wk), PwMS were tested for MS-related clinical and motor symptoms (Multiple Sclerosis Impact Scale-29 (MSIS-29), primary outcome), QoL (EuroQol Five Dimensions Questionnaire), symptoms of depression, gait and balance ability (Tinetti Assessment Tool), static and dynamic balance and fall risk (Berg Balance Scale), walking capacity (6-min walk test), and standing posturography on a force platform.

Patients were followed up for 2 years after 5 weeks of intensive care. Tests are performed every six months.

Detailed Description

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Conditions

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Multiple Sclerosis, Chronic Progressive Multiple Sclerosis, Primary Progressive

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Controll

No intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Training grp

Neurorehabilitation 2 years long intervention, administered daily, targeted postural instability, balance and mobility using at-limit intensity sensorimotor and visuomotor agility training

Group Type EXPERIMENTAL

Training groupe

Intervention Type OTHER

Using virtual training

PNF

2 years long, You have only treated patients with the PNF technique.

Group Type EXPERIMENTAL

PNF

Intervention Type OTHER

PNF technique was used

Spinning group

Patients developed endurance for 2 years. They worked using a spinning bike.

Group Type EXPERIMENTAL

Spinning grp

Intervention Type OTHER

They only worked with spinning bikes.

Balance

Neurorehabilitation 2 years long intervention, administered daily, targeted postural instability, balance

Group Type EXPERIMENTAL

Balance

Intervention Type OTHER

Balance development was done

Interventions

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Training groupe

Using virtual training

Intervention Type OTHER

PNF

PNF technique was used

Intervention Type OTHER

Spinning grp

They only worked with spinning bikes.

Intervention Type OTHER

Balance

Balance development was done

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Multiple Sclerosis
* instability problem

Exclusion Criteria

• Severe heart problems, severe demeanor, alcoholism, drug problems
Minimum Eligible Age

35 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Somogy Megyei Kaposi Mór Teaching Hospital

OTHER

Sponsor Role lead

Responsible Party

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Tollár József

Dr. József Tollár, Head of Neurorehabilitation ,7400 Kaposvár, Tallián Gy. u 20-32

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Somogy Megyei Kaposi Mór Oktató Kórház

Kaposvár, Somogy County, Hungary

Site Status

Countries

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Hungary

Related Links

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Other Identifiers

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IKEB2020/08

Identifier Type: -

Identifier Source: org_study_id

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