Study to Learn More About Safety of Aflibercept Injection in Japanese Patients With Neovascular Glaucoma (NVG)

NCT ID: NCT04519619

Last Updated: 2026-02-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

480 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-11-27

Study Completion Date

2028-06-30

Brief Summary

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This is a prospective, observational, multi-center and post-authorization safety study that includes patients with a diagnosis of Neovascular Glaucoma. The investigator will have made the decision to use Eylea for treatment.

The objective of this study is to assess safety and effectiveness of Eylea using in real clinical practice. Patients will be followed for a time period of 6 months from start of Eylea treatment or until it is no longer possible (e.g. lost to follow-up). In total, 480 patients will be recruited. For each patient, data are collected as defined in the electronic case report form (eCRF) at the initial visit, follow-up visit and final visit, either by routine clinical visits (as per investigators routine practice).

Detailed Description

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Conditions

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Neovascular Glaucoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Aflibercept (Eylea, BAY86-5321)

Decision of Eylea treatment is made by attending investigators according to the Japanese Package Insert

Aflibercept (Eylea, BAY86-5321)

Intervention Type DRUG

Administration by intravitreal injection

Interventions

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Aflibercept (Eylea, BAY86-5321)

Administration by intravitreal injection

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of NVG
* Patients who have received IVT-AFL treatment according to Japanese labeling.

Exclusion Criteria

* Patients who are contraindicated based on approved label
* Diagnosis of other indication
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Many locations

Multiple Locations, , Japan

Site Status RECRUITING

Countries

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Japan

Central Contacts

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Bayer Clinical Trials Contact

Role: CONTACT

(+)1-888-84 22937

Other Identifiers

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21220

Identifier Type: -

Identifier Source: org_study_id

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