Can MicroRNA's Predict Multicentricity in Breast Cancer?

NCT ID: NCT04516330

Last Updated: 2020-08-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

57 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-28

Study Completion Date

2019-04-30

Brief Summary

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The aim of this study is to determine if microRNA's have role in predicting multicentricity in breast cancer. If a specific microRNA will be found to be related with multicentricity, it will help us to make appropriate decisions on the treatment of patients with multicentric breast cancer.

Detailed Description

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In the study that will be held at Bezmialem Vakif University Medical Faculty, General Surgery Department, 20 unifocal and 20 multifocal breast cancer patients will be included. Tissues will be taken from both tumoral and normal breast tissues and they will be saved in microRNA later solution under -80°C. Then, 84 microRNA's will be studied in these tissues to see if they express any of these microRNA's.

Conditions

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Multicentric Breast Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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unifocal breast cancer

patients having unifocal breast cancer

Group Type ACTIVE_COMPARATOR

miRNA

Intervention Type GENETIC

miRNA's expressed in breast cancer

multicentric breast cancer

patients having multicentric breast cancer

Group Type ACTIVE_COMPARATOR

miRNA

Intervention Type GENETIC

miRNA's expressed in breast cancer

Interventions

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miRNA

miRNA's expressed in breast cancer

Intervention Type GENETIC

Eligibility Criteria

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Inclusion Criteria

1. Having breast cancer
2. Having no other malignancy
3. Female patient

Exclusion Criteria

1. Having other malignancy
2. Under 18 years old
3. Male patient
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Bezmialem Vakif University

OTHER

Sponsor Role lead

Responsible Party

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Yeliz Emine Ersoy

Assoc. Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Bezmialem Vakif University

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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MCBC-MIR

Identifier Type: -

Identifier Source: org_study_id

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