CytoSorb in Patients With Liver Failure

NCT ID: NCT04511507

Last Updated: 2021-09-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

35 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-02-10

Study Completion Date

2021-08-30

Brief Summary

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Hemoadsorption has been demonstrated to improve liver functional tests in patients with liver failure. The present study investigates the effects of three consecutive sessions of hemoadsorption, performed in accordance to the local protocol for treating patients with acute liver failure, on liver functional tests, severity scores and 30-days mortality. Paraclinical results and severity scores were obtained before and after the three consecutive sessions.

Detailed Description

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Conditions

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Liver Dysfunction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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liver failure

patients diagnosed with acute liver failure or acute on chronic liver failure in accordance with national guidelines who require 3 consecutive sessions of hemoadsorption

hemoadsorption

Intervention Type PROCEDURE

three consecutive sessions of hemoadsorption in patients with liver failure

Interventions

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hemoadsorption

three consecutive sessions of hemoadsorption in patients with liver failure

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients with acute liver failure or acute on chronic liver failure who require hemoadsorption in accordance with local guidelines

Exclusion Criteria

* unsigned informed consent
* duration of therapy under 12 hours
* death before the three consecutive sessions
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Institutul Clinic Fundeni

OTHER

Sponsor Role lead

Responsible Party

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Popescu Mihai

Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dana Tomescu, Prof

Role: STUDY_CHAIR

Fundeni Clinical Institute

Locations

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Fundeni Clinical Institute

Bucharest, , Romania

Site Status

Countries

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Romania

Other Identifiers

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Cyto-ALF

Identifier Type: -

Identifier Source: org_study_id

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