Evaluation of the Retinal Health Monitoring System Thickness Module

NCT ID: NCT04499703

Last Updated: 2021-02-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-11-11

Study Completion Date

2021-01-25

Brief Summary

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Evaluate the ability and accuracy of the Retinal Health Monitoring System - Retinal Thickness Module (RHMS - RTM).

Detailed Description

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Evaluation of the Retinal Health Monitoring System - Retinal Thickness Module in subjects with normal macular thickness and subjects with center-involving macular edema.

Conditions

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Macular Edema Macular Degeneration

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1

Subjects with normal macular thickness in one or both eyes.

RHMS-RTM

Intervention Type DEVICE

Assessment of retinal thickness

SD-OCT

Intervention Type DIAGNOSTIC_TEST

Assessment of retinal structure

Group 2

Subjects with center-involving macular edema due to wAMD in one or both eyes

RHMS-RTM

Intervention Type DEVICE

Assessment of retinal thickness

SD-OCT

Intervention Type DIAGNOSTIC_TEST

Assessment of retinal structure

Group 3

Subjects with center-involving macular edema due to DR or RVO in one or both eyes

RHMS-RTM

Intervention Type DEVICE

Assessment of retinal thickness

SD-OCT

Intervention Type DIAGNOSTIC_TEST

Assessment of retinal structure

Interventions

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RHMS-RTM

Assessment of retinal thickness

Intervention Type DEVICE

SD-OCT

Assessment of retinal structure

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Handheld swept source (SS) optical coherence tomography (OCT)

Eligibility Criteria

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Inclusion Criteria

1. Age ≥50.
2. Corrected visual acuity (VA) of 20/125 or better, in the study eye(s)
3. Media clarity, undilated pupil size, and subject cooperation sufficient to obtain adequate OCT B-scans in the study eye(s)
4. Able to perform self-testing of retinal thickness with the RHMS-RTM after training
5. Able and willing to provide written informed consent before undergoing any study-related procedures
6. Group 1: Macula with normal thickness \[central subfield thickness (CST): \<305μm in women, and \<320μm in men as measured by Heidelberg Spectralis SD-OCT in at least one eye. Patients diagnosed with dry AMD are eligible for enrollment into Group 1. No history of wAMD, DR, or RVO in either eye
7. Group 2 and Group 3, in at least one and the same eye: History of center-involving macular edema due to wAMD (Group 2); or DR or RVO (Group 3); Macular edema on SD-OCT with CST ≥305 μm in women, and ≥320μm in men as measured by Heidelberg Spectralis SD-OCT.

Exclusion Criteria

1. History of corneal refractive surgery \[e.g., laser-assisted in situ keratomileusis (LASIK), photorefractive keratectomy (PRK), radial keratotomy (RK)\] in the study eye(s)
2. History of epiretinal membrane, vitreomacular traction, or macular hole in the study eye(s)
3. Participation in any study using an investigational drug within 30 days of screening or an investigational device within 60 days of screening
4. Refractive error within defined limits
5. History of photocoagulation laser scar or other retinal scar in the central 3 mm of the macula, in the study eye(s)
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Kubota Vision Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marion Munk, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Inselspital, University Hospital Bern

Locations

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Inselspital, University Hospital Bern, Department of Ophthalmology

Bern, , Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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SCT-202 D

Identifier Type: -

Identifier Source: org_study_id

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