Study Evaluating Retinal Health Monitoring System Thickness Module

NCT ID: NCT04428242

Last Updated: 2021-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-30

Study Completion Date

2020-07-31

Brief Summary

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Evaluate the ability and accuracy of the Retinal Health Monitoring System - Retinal Thickness Module (RHMS - RTM).

Detailed Description

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Evaluation of the Retinal Health Monitoring System - Retinal Thickness Module in subjects with normal macular thickness and subjects with center-involving macular edema.

Conditions

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Macular Edema Macular Degeneration

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1

Subjects with normal macular thickness in one or both eyes.

RHMS-RTM

Intervention Type DEVICE

Assessment of retinal thickness.

SD-OCT

Intervention Type DIAGNOSTIC_TEST

Assessment of retinal structure.

Group 2

Subjects with center-involving macular edema due to w/AMD in one or both eyes.

RHMS-RTM

Intervention Type DEVICE

Assessment of retinal thickness.

SD-OCT

Intervention Type DIAGNOSTIC_TEST

Assessment of retinal structure.

Group 3

Subjects with center-involving macular edema due to DR or RVO in one or both eyes.

RHMS-RTM

Intervention Type DEVICE

Assessment of retinal thickness.

SD-OCT

Intervention Type DIAGNOSTIC_TEST

Assessment of retinal structure.

Interventions

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RHMS-RTM

Assessment of retinal thickness.

Intervention Type DEVICE

SD-OCT

Assessment of retinal structure.

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Handheld swept source (SS) optical coherence tomography (OCT)

Eligibility Criteria

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Inclusion Criteria

1. Corrected visual acuity (VA) of 20/100 or better, in the study eye(s)
2. Media clarity, undilated pupil size, OCT-B scans, axial length measurements in the study eye(s)
3. Able to perform self-testing of retinal thickness with the RHMS-RTM after training
4. Able and willing to give informed consent
5. Group 1:

1. Macula with normal thickness \[central subfield thickness (CST) below 305 microns as measured by SD-OCT\] in at least one eye
2. Patients with dry AMD are eligible for enrollment into Group 1
3. No history of wet AMD, DR, or RVO in either eye
6. Group 2 and Group 3 (in at least one or the same eye):

1. History of center-involving macular edema due to wet AMD (Group 2); or DR or RVO (Group 3)
2. Macular edema on SD-OCT with CST ≥ 305 microns

Exclusion Criteria

1. History of corneal refractive surgery, photorefractive keratectomy, radial keratotomy, in the study eye
2. History of epiretinal membrane, vitreomacular traction, or macular hole in the study eye(s)
3. Participation in any study using an investigational drug within 30 days or screening or investigational device within 60 days of screening
4. Refractive error: spherical equivalent of \> 3 diopters of hyperopia or \> 6 diopters of myopia, or \> 2 diopters cylinder in the study eye(s)
5. History of photocoagulation laser scar or other retinal scar in the central 3 mm of the macula, in the study eye(s)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Kubota Vision Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jeff Gregory, MD

Role: STUDY_DIRECTOR

Kubota Vision Inc.

Locations

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Retinal Consultants Medical Group, Inc

Sacramento, California, United States

Site Status

Countries

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United States

Other Identifiers

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SCT-202

Identifier Type: -

Identifier Source: org_study_id

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