The Chinese Registration Study of Driver Ablation of Persistent Atrial Fibrillation.
NCT ID: NCT04489004
Last Updated: 2023-02-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
1298 participants
INTERVENTIONAL
2020-08-01
2022-12-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Driver ablation+CPVI
Driver ablation plus CPVI (circumferential pulmonary vein isolation)
Driver ablation+CPVI
Patients receive driver ablation and CPVI (circumferential pulmonary vein isolation).
Stepwise ablation
Stepwise ablation
Stepwise ablation
Patients receive stepwise ablation.
Interventions
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Driver ablation+CPVI
Patients receive driver ablation and CPVI (circumferential pulmonary vein isolation).
Stepwise ablation
Patients receive stepwise ablation.
Eligibility Criteria
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Inclusion Criteria
2. Persistent AF;
3. nonresponse or intolerance to ≥1 antiarrhythmic drug. -
Exclusion Criteria
2. Having significant valvular disease and/or prosthetic heart valve(s);
3. With myocardial infarction or stroke within 6 months of screening;
4. With Significant congenital heart disease;
5. Ejection fraction was \<40% measured by echocardiography;
6. Allergic to contrast media;
7. Contraindication to anticoagulation medications;
8. Severe pulmonary disease e.g. restrictive pulmonary disease, chronic obstructive disease (COPD);
9. Left atrial (LA) thrombus measured by pre-procedure transesophageal echocardiography;
10. Having any contraindication to right or left sided heart catheterization;
11. Previous atrial fibrillation ablation;
12. Presence of an implanted cardioverter-defibrillator;
13. Any cardiac surgery within the past 2 months;
14. Poor general health;
15. Life expectancy less than 6 months.
18 Years
80 Years
ALL
No
Sponsors
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Shanghai Chest Hospital
OTHER
Responsible Party
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Xu Liu
Professor, deputy director of cardiology department of Shanghai Chest Hospital
Locations
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Shanghai Chest Hospital
Shanghai, , China
Countries
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Other Identifiers
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Credit-AF
Identifier Type: -
Identifier Source: org_study_id
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