Left Atrium Substrate Based Ablation Plus Circumferential Pulmonary Vein Isolation to Treat Chronic Atrial Fibrillation

NCT ID: NCT01716143

Last Updated: 2012-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

87 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-03-31

Study Completion Date

2012-12-31

Brief Summary

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The purpose of this study is to determine whether left atrium substrate based ablation plus circumferential is effective in the treatment of persistent and long-standing atrial fibrillation.

Detailed Description

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Conditions

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Atrial Fibrillation

Keywords

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atrial fibrillation catheter ablation Mapping

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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catheter ablation

Group Type OTHER

radiofrequency catheter ablation

Intervention Type PROCEDURE

Interventions

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radiofrequency catheter ablation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

All persistent or permanent AF patients with refractory or intolerant to at least one Class 1 or Class 3 antiarrhythmic medication.

Exclusion Criteria

1. Patients with paroxysmal AF (self-terminating episodes lasting \< 7 day)
2. Patients who have had a previous AF ablation procedure
3. Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The First Affiliated Hospital with Nanjing Medical University

OTHER

Sponsor Role lead

Responsible Party

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Youquan Wei

Clinical Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Division of Cardiology, the First Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Minglong Chen, MD

Role: CONTACT

Phone: 0086-25-6813-6965

Email: [email protected]

Facility Contacts

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Minglong Chen, MD

Role: primary

References

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Yang G, Yang B, Wei Y, Zhang F, Ju W, Chen H, Li M, Gu K, Lin Y, Wang B, Cao K, Kojodjojo P, Chen M. Catheter Ablation of Nonparoxysmal Atrial Fibrillation Using Electrophysiologically Guided Substrate Modification During Sinus Rhythm After Pulmonary Vein Isolation. Circ Arrhythm Electrophysiol. 2016 Feb;9(2):e003382. doi: 10.1161/CIRCEP.115.003382.

Reference Type DERIVED
PMID: 26857907 (View on PubMed)

Other Identifiers

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2011-SR-014

Identifier Type: -

Identifier Source: org_study_id