The Reproducibility and Clinical Utility of an Abbreviated Fat Tolerance Test

NCT ID: NCT04437459

Last Updated: 2020-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-08

Study Completion Date

2019-07-31

Brief Summary

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This study aims to evaluate the reliability of a shortened fat tolerance test ("abbreviated fat tolerance test", or "AFTT") for measuring post-meal lipids in human blood. The reliability of the triglyceride results in this test are compared to the reliability of the glucose results from an oral glucose tolerance test (OGTT), a widely-used and clinically accepted metabolic test.

Detailed Description

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Conditions

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Dyslipidemias Metabolic Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Abbreviated Fat Tolerance Test

Group Type EXPERIMENTAL

High-fat shake

Intervention Type OTHER

Participant consumes a high-fat test shake. Blood is drawn before and 4 hours after this shake to measure triglycerides.

Oral Glucose Tolerance Test

Group Type ACTIVE_COMPARATOR

Pure glucose solution

Intervention Type OTHER

Participant consumes 75 grams of pure glucose. Blood is drawn before and 2 hours after this drink to measure glucose.

Interventions

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High-fat shake

Participant consumes a high-fat test shake. Blood is drawn before and 4 hours after this shake to measure triglycerides.

Intervention Type OTHER

Pure glucose solution

Participant consumes 75 grams of pure glucose. Blood is drawn before and 2 hours after this drink to measure glucose.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Free of chronic disease
* Normal (healthy) fasting glucose and triglycerides

Exclusion Criteria

* Presence of pace-maker
* Pregnant
* Using tobacco products
* Using medications or dietary supplements that could modify primary outcomes
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Oklahoma State University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sam R Emerson, PhD

Role: PRINCIPAL_INVESTIGATOR

Oklahoma State University

Locations

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Oklahoma State University

Stillwater, Oklahoma, United States

Site Status

Countries

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United States

Other Identifiers

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HS1844

Identifier Type: -

Identifier Source: org_study_id

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