Endo-Band: Endoscopic Band Ligation for Weight Loss

NCT ID: NCT04431232

Last Updated: 2024-08-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

5 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-01

Study Completion Date

2026-03-07

Brief Summary

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To the best of our knowledge, this is the first study to use endoscopic band ligation for weight loss. All ligatures will be performed in the gastric body starting at the distal body; 5 parallel rows, with the last one in the proximal body.The entire procedure can be completed in 30 min. Oxygen is used for endoscopic air insufflation.Endoscopy is performed using propofol for sedation.

Detailed Description

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The idea of band ligation of the gastric body is to induce multiple gastric ulcers that forms a fibrotic scars which can lead to marginal narrowing of the lumen; same as that occurred in the esophagus following band ligation of esophageal varices or in the antrum following band ligation of GAVE.

Conditions

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Obesity

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Band Ligation

Band ligation of gastric body for weight loss

Group Type EXPERIMENTAL

Endoscopic Band Ligation

Intervention Type DEVICE

Band ligation of the gastric body for weight loss

Interventions

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Endoscopic Band Ligation

Band ligation of the gastric body for weight loss

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* BMI \> 27

Exclusion Criteria

* Any contraindication for endoscopy
* Any gastric bleeding lesions
* Uncontrolled use of anticoagulants or NSAID's
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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El Katib Hospital

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Abeid

Consultant Gastroenterologist/ Bariatric Endoscopist Cairo University

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mohamed Abeid, MD

Role: PRINCIPAL_INVESTIGATOR

Endoscopy Unit Faculty of Medicine Cairo University

Locations

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El Katib Hospital (Celopatra Group)

Giza, Dokki, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Mohamed Abeid, MD

Role: CONTACT

+201001222254

Facility Contacts

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Mohamed Abeid, MD

Role: primary

01001222254

References

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Jirapinyo P, Thompson CC. Endoscopic gastric body plication for the treatment of obesity: technical success and safety of a novel technique (with video). Gastrointest Endosc. 2020 Jun;91(6):1388-1394. doi: 10.1016/j.gie.2020.01.030. Epub 2020 Jan 28.

Reference Type BACKGROUND
PMID: 32001332 (View on PubMed)

Keohane J, Berro W, Harewood GC, Murray FE, Patchett SE. Band ligation of gastric antral vascular ectasia is a safe and effective endoscopic treatment. Dig Endosc. 2013 Jul;25(4):392-6. doi: 10.1111/j.1443-1661.2012.01410.x. Epub 2012 Dec 17.

Reference Type BACKGROUND
PMID: 23808945 (View on PubMed)

Abeid M, Miller KA, Kaddah T, Zaitoun N. Outcome of Primary Obesity Surgery Endolumenal Procedure as Obesity Treatment in Private Practice Setting: an Intervention Study. Obes Surg. 2019 Apr;29(4):1364-1366. doi: 10.1007/s11695-018-03698-z. No abstract available.

Reference Type BACKGROUND
PMID: 30627991 (View on PubMed)

Other Identifiers

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MohamedAbeid1

Identifier Type: -

Identifier Source: org_study_id

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