A Study to Compare Two Techniques for Pain Control After Bariatric Surgery

NCT ID: NCT04427059

Last Updated: 2021-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

115 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-06-15

Study Completion Date

2021-07-07

Brief Summary

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The purpose of this study is to compare the postoperative pain and other clinical outcomes in patients who, during bariatric surgery, will be injected with a local anesthetic (Ropivacaine) through two different techniques.

Detailed Description

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Conditions

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Pain, Postoperative Bariatric Surgery Candidate

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Arm A - laparoscopic assisted TAP block

Patients will undergo the planned bariatric intervention according to the standard of treatment. A solution of 20 ml of the local anesthetic Ropivacaine (0.25%) is then injected for postoperative pain control according to the allocated procedure (TPA).

Group Type EXPERIMENTAL

Transversus Abdominis Plane (TAP) block

Intervention Type PROCEDURE

The laparoscopic-assisted Transversus Abdominis Plane (TAP) block will be done just after the optic trocar placement as follow: as landmarks we use the anterior axillary line, in the middle between the iliac crest and the costal margin. After insertion of the optic trocar the peritoneum is visualized. A 14 Gauge needle is inserted 2 cm cranially respect the taken landmark through the skin until the penetration of the internal and external oblique fascias, identified as sudden lowering of resistance. Laparoscopy allows to confirm that the needle did not pass the peritoneum.

A solution of 20 ml of Ropivacaine (0.25%) is then injected, observing the formation of a bulge posterior to the transversus abdominis muscle.

The procedure is then repeated identically on the contralateral side.

Arm B - PSI

Patients will undergo the planned bariatric intervention according to the standard of treatment. A solution of 20 ml of the local anesthetic Ropivacaine (0.25%) is then injected for postoperative pain control according to the allocated procedure (PSI).

Group Type ACTIVE_COMPARATOR

Port-Site Infiltration (PSI)

Intervention Type PROCEDURE

The Port-Site Infiltration (PSI) will be performed by infiltrating the subcutis and the skin at the trocar site before the trocar placements with a solution of local anesthetic (Ropivacaine 0.25%), a total of 40 ml will be administered.

Interventions

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Transversus Abdominis Plane (TAP) block

The laparoscopic-assisted Transversus Abdominis Plane (TAP) block will be done just after the optic trocar placement as follow: as landmarks we use the anterior axillary line, in the middle between the iliac crest and the costal margin. After insertion of the optic trocar the peritoneum is visualized. A 14 Gauge needle is inserted 2 cm cranially respect the taken landmark through the skin until the penetration of the internal and external oblique fascias, identified as sudden lowering of resistance. Laparoscopy allows to confirm that the needle did not pass the peritoneum.

A solution of 20 ml of Ropivacaine (0.25%) is then injected, observing the formation of a bulge posterior to the transversus abdominis muscle.

The procedure is then repeated identically on the contralateral side.

Intervention Type PROCEDURE

Port-Site Infiltration (PSI)

The Port-Site Infiltration (PSI) will be performed by infiltrating the subcutis and the skin at the trocar site before the trocar placements with a solution of local anesthetic (Ropivacaine 0.25%), a total of 40 ml will be administered.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients undergoing elective bariatric surgery
* age ≥ 18 years
* signed informed consent

Exclusion Criteria

* Pregnant or lactating women,
* known allergy to local anesthetics
* Chronic pain syndrome.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fabio Garofalo

OTHER

Sponsor Role lead

Responsible Party

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Fabio Garofalo

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Fabio Garofalo, MD

Role: PRINCIPAL_INVESTIGATOR

EOC Surgeery Department

Locations

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Ospedale Regionale di Lugano, Civico e Italiano

Lugano, , Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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ORL-CHIR-008

Identifier Type: -

Identifier Source: org_study_id

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