Severe Acute Respiratory Syndrome-Coronavirus-2 and Loss of Autonomy in the Elderly

NCT ID: NCT04414319

Last Updated: 2023-07-20

Basic Information

• Recruitment Status: TERMINATED
• Total Enrollment: 170 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-04-15
• Study Completion Date: 2023-04-13

Brief Summary

In most diseases, older people have less typical symptomatology than that described for younger people. The investigators therefore hypothesize that within the framework of coronavirus disease 19, the clinical pictures in the elderly will present specificities that will need to be described. Moreover, since infection by the severe acute respiratory syndrome (SARS-CoV-2) virus is new to humans, the investigators do not yet have sufficient information on the fate of the elderly, in terms of loss of autonomy, rehospitalization, institutionalization, mortality, etc. the investigators therefore assume that the clinical pictures in the elderly will present specificities that will need to be described. The investigators hypothesize that an acute infection of this type will have short-, medium-, and long-term repercussions in the elderly.

Detailed Description

The question of the outcome of elderly populations in the immediate aftermath of the epidemic and at a distance from it are essential to measure the effectiveness of the medical care that has been undertaken, but also to adapt the response to the specific problems of the elderly population. It is likely that the older, more fragile population will take longer to recover from the epidemic than the younger population because their functional reserves prior to coronavirus disease 19 are lower. In addition, the possible consequences of containment must be added to the burden of co-morbidities and dependence prior to the epidemic. Containment is synonymous with a restriction in social relationship, and sometimes a reduction in the support provided on a daily basis to frail or even dependent elderly people. Moreover, containment alone may be responsible for the onset or worsening of pathologies.

In most diseases, older people have less typical symptomatology than that described for younger people. The investigators therefore hypothesize that within the framework of coronavirus disease 19, the clinical pictures in the elderly will present specificities that will need to be described. Moreover, since infection by the SARS-CoV-2 virus is new to humans, the investigators do not yet have sufficient information on the fate of the elderly, in terms of loss of autonomy, rehospitalization, institutionalization, mortality, etc. The investigators therefore assume that the clinical pictures in the elderly will present specificities that will need to be described. The investigators hypothesize that an acute infection of this type will have short-, medium-, and long-term repercussions in the elderly.

Conditions

SARS-CoV 2

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• 70 years of age or older;
• Hospitalized in a short stay or a rehabilitation geriatric wards at one of the participating centers;
• Positive by Reverse Transcriptase-Polymerase Chain Reaction for severe acute respiratory syndrome (SARS-CoV-2) coronavirus or be considered to have SARS-CoV-2 coronavirus based on lung CT data and physician opinion;
• Formal consent to answer the questionnaire or, in the event of inability to give consent, consent obtained from the trusted third party;
• Affiliation to a social security scheme.

Exclusion Criteria

• Patient under formal guardianship or trusteeship.

• Minimum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital Center of Martinique

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Moustapha DRAME, PHD

Role: STUDY_DIRECTOR

Unversity hospital of Martinique

Locations

University hospital of Rennes

Rennes, , France

Va de Lys-Ramsay Gds group Clinic

Tourcoing, , France

Hopsital of Valenciennes

Valenciennes, , France

University hospital of Guadeloupe

Les Abymes, , Guadeloupe

University hospital of Martinique

Fort-de-France, , Martinique

Countries

France; Guadeloupe; Martinique

Other Identifiers

20_RIPH3-02

Identifier Type: -

Identifier Source: org_study_id