Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control

NCT ID: NCT04399707

Last Updated: 2020-05-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-01-29

Study Completion Date

2021-05-31

Brief Summary

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Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.

Detailed Description

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Conditions

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Transcutaneous Electric Nerve Stimulation Analgesia Cesarean Section

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants are randomized to one of three groups in parallel for the duration of the study
Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Active TENS Unit

Group Type ACTIVE_COMPARATOR

Transcutaneous electrical nerve stimulation (TENS) unit

Intervention Type DEVICE

Patients will be randomized to active TENS unit, placebo TENS unit, or no TENS unit

Placebo TENS Unit

Group Type PLACEBO_COMPARATOR

Placebo transcutaneous electrical nerve stimulation (TENS) unit

Intervention Type DEVICE

Patients will be randomized to active TENS unit, placebo TENS unit, or no TENS unit

No TENS Unit

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Transcutaneous electrical nerve stimulation (TENS) unit

Patients will be randomized to active TENS unit, placebo TENS unit, or no TENS unit

Intervention Type DEVICE

Placebo transcutaneous electrical nerve stimulation (TENS) unit

Patients will be randomized to active TENS unit, placebo TENS unit, or no TENS unit

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

\- Women undergoing scheduled or non-urgent cesarean section

Exclusion Criteria

* Non-English speaking
* Subjects with a history of chronic pain or chronic opioid use
* Pre-operative use of opioids for more than 1 week in the preceding 6 months
* Previous exposure to the TENS unit
* Women with an allergy or contraindication to narcotics/NSAIDs/acetaminophen
* Subjects who had a midline vertical skin incision during this operation
* Subjects who did not receive intrathecal opioids at the time of their cesarean delivery
* Adhesive allergies
* Subjects with a pacemaker (due to the unknown effects of the TENS on the electrical activity of the heart)
* Intraoperative general anesthesia
* Inability to consent to the study
* Postpartum tubal ligation
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hawaii Pacific Health

OTHER

Sponsor Role lead

Responsible Party

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Kelly Yamasato, MD

Physician, Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kelly Yamasato

Role: PRINCIPAL_INVESTIGATOR

Physician

Locations

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Nicole Kurata

Honolulu, Hawaii, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Nicole Kurata

Role: CONTACT

(808)577-3344

Kelly Yamasato

Role: CONTACT

Facility Contacts

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Nicole Kurata

Role: primary

808-577-3344

References

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Bateman BT, Franklin JM, Bykov K, Avorn J, Shrank WH, Brennan TA, Landon JE, Rathmell JP, Huybrechts KF, Fischer MA, Choudhry NK. Persistent opioid use following cesarean delivery: patterns and predictors among opioid-naive women. Am J Obstet Gynecol. 2016 Sep;215(3):353.e1-353.e18. doi: 10.1016/j.ajog.2016.03.016. Epub 2016 Mar 17.

Reference Type BACKGROUND
PMID: 26996986 (View on PubMed)

Desantana JM, Sluka KA, Lauretti GR. High and low frequency TENS reduce postoperative pain intensity after laparoscopic tubal ligation: a randomized controlled trial. Clin J Pain. 2009 Jan;25(1):12-9. doi: 10.1097/AJP.0b013e31817d1070.

Reference Type BACKGROUND
PMID: 19158541 (View on PubMed)

Bjordal JM, Johnson MI, Ljunggreen AE. Transcutaneous electrical nerve stimulation (TENS) can reduce postoperative analgesic consumption. A meta-analysis with assessment of optimal treatment parameters for postoperative pain. Eur J Pain. 2003;7(2):181-8. doi: 10.1016/S1090-3801(02)00098-8.

Reference Type BACKGROUND
PMID: 12600800 (View on PubMed)

Chou R, Gordon DB, de Leon-Casasola OA, Rosenberg JM, Bickler S, Brennan T, Carter T, Cassidy CL, Chittenden EH, Degenhardt E, Griffith S, Manworren R, McCarberg B, Montgomery R, Murphy J, Perkal MF, Suresh S, Sluka K, Strassels S, Thirlby R, Viscusi E, Walco GA, Warner L, Weisman SJ, Wu CL. Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council. J Pain. 2016 Feb;17(2):131-57. doi: 10.1016/j.jpain.2015.12.008.

Reference Type BACKGROUND
PMID: 26827847 (View on PubMed)

Dowswell T, Bedwell C, Lavender T, Neilson JP. Transcutaneous electrical nerve stimulation (TENS) for pain relief in labour. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD007214. doi: 10.1002/14651858.CD007214.pub2.

Reference Type BACKGROUND
PMID: 19370680 (View on PubMed)

Kurata NB, Ghatnekar RJ, Mercer E, Chin JM, Kaneshiro B, Yamasato KS. Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Birth Pain Control: A Randomized Controlled Trial. Obstet Gynecol. 2022 Aug 1;140(2):174-180. doi: 10.1097/AOG.0000000000004798. Epub 2022 Jul 6.

Reference Type DERIVED
PMID: 35852266 (View on PubMed)

Other Identifiers

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2019-035

Identifier Type: -

Identifier Source: org_study_id

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