Analgesic Efficacy of Different Nerve Blocks in Postoperative Cesarean Section

NCT ID: NCT06088420

Last Updated: 2025-04-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-15

Study Completion Date

2025-04-05

Brief Summary

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comparing analgesic efficacy of different nerve blocks on post operative cesarean sections.

Detailed Description

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Analgesic efficacy of Erector Spinae, Quadratus Lumborum and Intrathecal Morphine for post operative pain relief after cesarean section,

Conditions

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Post Operative Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Intrathcal Morphine Group

Intrathecal morphine administration for post operative pain relief after cesarean section

Group Type ACTIVE_COMPARATOR

Intrathcal Morphine Group

Intervention Type PROCEDURE

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs(10-12 mg 0.5% hyperbaric bupivacaine)

Quadratus Lumborum nerve block group

Quadratus Lumborum nerve block administration for post operative pain relief after cesarean section

Group Type ACTIVE_COMPARATOR

Quadratus Lumborum nerve block(QL) group

Intervention Type PROCEDURE

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs (10-12 mg 0.5% hyperbaric bupivacaine) + bilateral QL block by injecting 20 ml of 0.25% isobaric bupivacaine bolus with 4 mg ) dexamethasone as an adjuvant

Erector Spinae nerve block group

Erector Spinae nerve block administraion for post operative pain relief after cesarean section

Group Type ACTIVE_COMPARATOR

Erector Spinae nerve block (ESP)group

Intervention Type PROCEDURE

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs (10-12 mg 0.5% hyperbaric bupivacaine) + bilateral ESP block by injecting 20 ml of 0.25% isobaric bupivacaine bolus with 4 mg ) dexamethasone as an adjuvant

Interventions

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Intrathcal Morphine Group

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs(10-12 mg 0.5% hyperbaric bupivacaine)

Intervention Type PROCEDURE

Quadratus Lumborum nerve block(QL) group

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs (10-12 mg 0.5% hyperbaric bupivacaine) + bilateral QL block by injecting 20 ml of 0.25% isobaric bupivacaine bolus with 4 mg ) dexamethasone as an adjuvant

Intervention Type PROCEDURE

Erector Spinae nerve block (ESP)group

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs (10-12 mg 0.5% hyperbaric bupivacaine) + bilateral ESP block by injecting 20 ml of 0.25% isobaric bupivacaine bolus with 4 mg ) dexamethasone as an adjuvant

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* 18-40 years old
* more or equal 37 weeks of gestation
* ASA 1,2
* Elective cesarean delivery

Exclusion Criteria

* Patient refusal
* inability to cooperate with or understand the study
* local infection.
* bleeding disorder
* known anaphylaxis to any drug used in the trial
* ASA physical status more than 2
* emergency operations
* chronic opioid use (opioid use in the past 3 months)
* Neurologic deficit or disorder
* contraindication to regional anesthesia.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Mahmoud Mamdouh Ekram

principal investigator.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Mahmoud Mamdouh Ekram

Asyut, Manfalout, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Ghada Abo Elfadl, MD

Role: CONTACT

01005802086

Ghada Abo Elfadl

Role: CONTACT

01005802086

Facility Contacts

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Ghada Abo Elfadl, prof

Role: primary

01005802086

Other Identifiers

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17101962

Identifier Type: -

Identifier Source: org_study_id

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