Cardiovascular Imaging Registry of Canada

NCT ID: NCT04367220

Last Updated: 2024-03-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

45000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-31

Study Completion Date

2030-08-31

Brief Summary

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A multi-site, multi-modality prospective observational clinical outcomes study focussed on the development of phenotype-dirven risk prediction modelling in patients with known or suspected cardiovascular disease.

Detailed Description

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The Cardiovascular Imaging Registry of Canada (CIROC) was conceived to provide a common standardized architecture for the collection of clinically reported imaging biomarkers, demographic information, resource utilization and clinical outcomes among patients referred to non-invasive cardiac imaging. The Registry was designed to assess the feasibility of implementing personalized care strategies through automated high quality data collection and patient engagement.

The CIROC Registry was launched with inaugural focus on Cardiac MRI base phenotyping, however has evolved to encompass cardiac CTA and echocardiography. Clinically referred patients are engaged by automated, tablet-based tools to collect informed consent and deploy standardized patient health assessments. Standardized reporting of disease features are captured using bespoke reporting tools. All patients are prospectively followed for a period of 10-years using linkage to administrative health data, inclusive of ICD-coded events, laboratory test results, ECG and vital statistics.

Conditions

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Cardiovascular Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with known or suspected cardiovascular disease

All patients with known or suspected cardiovascular disease are studied with a-priori stratification of specific disease-based cohorts.

Diagnostic testing performed as per routine care

Intervention Type DIAGNOSTIC_TEST

Interventions

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Diagnostic testing performed as per routine care

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* All patients referred for hospital-based cardiac imaging services

Exclusion Criteria

* Failure or provide informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alberta Health services

OTHER

Sponsor Role collaborator

University of Calgary

OTHER

Sponsor Role lead

Responsible Party

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James White

MD, FRCP(C) Director - Stephenson Cardiac Imaging Centre

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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James White

Role: PRINCIPAL_INVESTIGATOR

Director of Stephenson Cardiac Imaging Centre

Locations

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Foothills Medical Centre

Calgary, Alberta, Canada

Site Status RECRUITING

South Health Campus

Calgary, Alberta, Canada

Site Status RECRUITING

Peter Lougheed Hospital

Calgary, Alberta, Canada

Site Status RECRUITING

Rockyview Hospital

Calgary, Alberta, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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James White

Role: CONTACT

403-944-2805

Sandra Rivest

Role: CONTACT

403-944-1961

Facility Contacts

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James A White, MD

Role: primary

James A White, MD

Role: primary

James A White, MD

Role: primary

James A White, MD

Role: primary

References

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Purmah Y, Lei LY, Dykstra S, Mikami Y, Cornhill A, Satriano A, Flewitt J, Rivest S, Sandonato R, Seib M, Lydell CP, Howarth AG, Heydari B, Merchant N, Bristow M, Fine N, Gaztanaga J, White JA. Right Ventricular Ejection Fraction for the Prediction of Major Adverse Cardiovascular and Heart Failure-Related Events: A Cardiac MRI Based Study of 7131 Patients With Known or Suspected Cardiovascular Disease. Circ Cardiovasc Imaging. 2021 Mar;14(3):e011337. doi: 10.1161/CIRCIMAGING.120.011337. Epub 2021 Mar 16.

Reference Type DERIVED
PMID: 33722059 (View on PubMed)

Other Identifiers

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REB13-0902

Identifier Type: -

Identifier Source: org_study_id

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