New Bioactive Restorative Material vs GIC in Restoration of Proximal Lesions

NCT ID: NCT04365283

Last Updated: 2020-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-01

Study Completion Date

2022-05-01

Brief Summary

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ACTIVA BioACTIVE products are allegedly the first dental resins with a bioactive ionic resin matrix, shock-absorbing rubberized resin component, and reactive ionomer glass fillers that mimic the physical and chemical properties of natural teeth. These bioactive materials actively participate in the cycles of ionic exchange that regulate the natural chemistry of our teeth and saliva and contribute to the maintenance of tooth structure and oral health. They are claimed to have the strength, esthetics and physical properties of composites and are more bioactive than glass ionomers, combining the best attributes of both materials without compromising either one.

Detailed Description

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High caries risk patients are those who have high DMF index, high sugar intake, poor oral hygiene, inadequate salivary flow, low pH level, as well as deficient fluoride exposure.

Therefore, their management has to be adequate and proper. To overcome these setbacks, glass ionomer cements that have advantages such as similar coefficient of thermal expansion to natural tooth tissue, physicochemical adhesion to tooth structure, biocompatability, fluoride release, low shrinkage and low marginal leakage as well as anticaries properties and increased remineralization interproximally ,which is especially beneficial in high risk caries patients, have been considered as an alternative restorative material to composite and amalgam. To enhance the mechanical properties of GIs, their constituents have been modified Comparatively, resin-modified glass ionomer (RMGIs) with a longer working time, faster setting, higher early strength, and improved appearance and translucency. Unfortunately, the RMGI's mechanical properties of are different to resin composites. Progressive development of material sciences has resulted in the introduction of bioactive restorative materials. These materials can activate a tissue repair mechanism for or synthesis and elicit a response from teeth and surrounding environment. ACTIVA BioACTIVE products are allegedly the first dental resins with a bioactive ionic resin matrix, shock-absorbing rubberized resin component, and reactive ionomer glass fillers that mimic the physical and chemical properties of natural teeth. These bioactive materials actively participate in the cycles of ionic exchange that regulate the natural chemistry of our teeth and saliva and contribute to the maintenance of tooth structure and oral health. They are claimed to have the strength, esthetics and physical properties of composites and are more bioactive than glass ionomers, combining the best attributes of both materials without compromising either one.

Activa Presto light-cured material from Pulpdent is the company's latest product that features biomimicry as Activa Bioactive dual-cured material. The material diffuses fluoride, calcium, and phosphate ions that fortify the saliva and help replace essential minerals that are lost in the decay process. This highly esthetic, light-cured resin contains these ions in a stackable resin matrix that holds its shape and does not slump. This durable product is resistant to fracturing and wear, especially so on the thin areas of enamel bevels, and is indicated for all restorative procedures replacing dentin and/or enamel, anterior or posterior.

Conditions

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Randomized Clinical Trial

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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New Bioactive Restorative Material

ACTIVA Presto restorative material

Group Type EXPERIMENTAL

New Bioactive Restorative Material (ACTIVA Presto)

Intervention Type PROCEDURE

New Bioactive Restorative Material

High Viscosity Glass Hybrid Reinforced Glass Ionomer

EQUIA Forte restorative material

Group Type ACTIVE_COMPARATOR

High Viscosity Glass Hybrid Reinforced Glass Ionomer (EQUIA Forte)

Intervention Type OTHER

High Viscosity Glass Hybrid Reinforced Glass Ionomer

Interventions

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New Bioactive Restorative Material (ACTIVA Presto)

New Bioactive Restorative Material

Intervention Type PROCEDURE

High Viscosity Glass Hybrid Reinforced Glass Ionomer (EQUIA Forte)

High Viscosity Glass Hybrid Reinforced Glass Ionomer

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Proximal lesions in posterior premolars and molars and Age 20-40 years

Exclusion Criteria

Low caries risk patients. Lack of compliance Class V in molars Systemic diseases or severe medical complications. Pregnancy. Rampant caries Disabilities
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rana Ayman Kamal

OTHER

Sponsor Role lead

Responsible Party

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Rana Ayman Kamal

Resident, Conservative Dentistry Department, Faculty of Dentistry, Cairo University

Responsibility Role SPONSOR_INVESTIGATOR

Central Contacts

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Rana Kamal, BDS

Role: CONTACT

01226000747 ext. 12

Other Identifiers

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25091992

Identifier Type: -

Identifier Source: org_study_id

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