Cardiotoxicity in Breast Cancer Patients Treated With Proton or Photon Radiotherapy: A RadComp Companion Study
NCT ID: NCT04361240
Last Updated: 2025-07-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
172 participants
OBSERVATIONAL
2020-08-01
2025-05-29
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Ancillary Cohort
No Intervention: Subjects will be followed before, during and for up to 1 year after radiation with echocardiogram, blood draw, and symptoms and activity survey.
Proton vs Photon Radiation
Assignment to proton vs photon by randomization on RadComp parent study.
Interventions
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Proton vs Photon Radiation
Assignment to proton vs photon by randomization on RadComp parent study.
Eligibility Criteria
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Inclusion Criteria
* Willing and able to provide written consent
Exclusion Criteria
* Non-diagnostic echocardiography windows as assessed on local read.
21 Years
ALL
No
Sponsors
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National Heart, Lung, and Blood Institute (NHLBI)
NIH
Abramson Cancer Center at Penn Medicine
OTHER
Responsible Party
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Principal Investigators
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Bonnie Ky, MD, MSCE
Role: PRINCIPAL_INVESTIGATOR
University of Pennsylvania
Locations
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University of Alabama
Birmingham, Alabama, United States
Northwestern Medicine
Warrenville, Illinois, United States
Johns Hopkins
Baltimore, Maryland, United States
Memorial Sloan Kettering Cancer Center
New York, New York, United States
Abramson Cancer Center at University of Pennsylvania
Philadelphia, Pennsylvania, United States
University of Washington
Seattle, Washington, United States
Countries
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Other Identifiers
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UPCC 17119
Identifier Type: -
Identifier Source: org_study_id
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