Blood Pressure Variability and Cardiovascular Disease Events in Patients With Hypertension

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

1736 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-07-14

Study Completion Date

2019-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Cardiovascular Disease (CV) including stroke is the leading cause of death in Malaysia Hypertension is a major contributor to this. Prevalence of hypertension in Malaysia is high (42%) in adults age 30 years or older. Besides the actual blood pressure (BP) level recently, blood pressure variability (BPV) has been recognized as an independent and strong predictor of CV events especially strokes. However, data on the BP variability and its relationship to CV events is very limited in Asia, particularly in Malaysia. Hence the investigators aim to study BPV and its relationship to CV events in treated hypertensive patients

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of Blood Pressure on Myocardial Work in Patients With Hypertension

NCT05062811

Hypertension; Heart Disease, Hypertensive

UNKNOWN

Prognostic Value of Plasma Biomarkers Among Patients With Hypertension

NCT04107584

Hypertension

UNKNOWN

Long-term of Remote Ischemic Preconditioning in Patients With Mild Hypertension

NCT04753840

Hypertension

RECRUITING NA

Mechanisms Underlying Abnormal Ambulatory BP Patterns

NCT00005346

Cardiovascular Diseases Heart Diseases Hypertension

COMPLETED

Adolescent Blood Pressure Variation and Ventricular Mass

NCT00005200

Cardiovascular Diseases Heart Diseases Hypertension

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This will be a cross-sectional study on patients with hypertension. The 10-year retrospective data on BP, treatment, biochemical changes, kidney function and CV events will be extracted from patient records.

Eligible patients who have given written informed consent will be given a questionnaire capturing data of their socio-demographic status, weight, height and BP measured.

Those agreeable to measure their own BP at home 3 times a day for a week will be loaned a BP device to measure their own BP at home. The home BP readings will be recorded onto a provided form and returned to the investigators.

Data will be analysed to

1. determine BPV of the clinic visit-to-visit BPV (long tem BPV)
2. determine the day to day BPV (short term BPV)
3. examine the BPV to CV events, kidney function, cognition
4. determine the prevalence of white coat and masked hypertension
5. determine the level of control of BP
6. examine the relationship of ownership of home BP devices to control and satisfaction of treatment

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Blood Pressure Variability Hypertension Cardiovascular Diseases

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

non-interventional

No intervention

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients on treatment for hypertension of at least 3 years
* Patients who consent to the study

Exclusion Criteria

* those unable to give consent
* recent (less than 6 months) of cardiovascular events (stroke, heart attack, heart failure)
* patients on dialysis
* patients with end stage kidney failure

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No