Pre-hospital Post ROSC Care: Are we Achieving Our Targets?

NCT ID: NCT04339257

Last Updated: 2020-05-05

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 175 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-05-31
• Study Completion Date: 2021-11-30

Brief Summary

Rational: Out of hospital cardiac arrest is a devastating event with a high mortality. Survival rates have increased over the last years, with the availability of AED's and public BLS. Previous studies have shown that deranged physiology after return of spontaneous circulation (ROSC) is associated with a worse neurological outcome. Good quality post-arrest care is therefore of utmost importance.

Objective: To determine how often prehospital crews (with their given skills set) encounter problems meeting optimal post-ROSC targets in patients suffering from OHCA, and to investigate if this can be predicted based on patient-, provider- or treatment factors.

Study design: Prospective cohort study of all patients attended by the EMS services with an OHCA who regain ROSC and are transported to a single university hospital, in order to identify those patients with a ROSC after a non-traumatic OHCA who had deranged physiology and/or complications from OHCA EMS personnel was unable to prevent/deal with in the prehospital environment.

Study population: Patients, >18 years, transported by the EMS services to the ED of the University Hospital Groningen (UMCG) with a ROSC after OHCA in a 1 year period

Main study parameters/endpoints: Primary endpoint of our study is the percentage of OHCA patients with a prehospital ROSC who arrive in hospital with either a deranged physiology or with complications from OHCA EMS personnel was unable to deal with.

Conditions

Out-Of-Hospital Cardiac Arrest; Post Cardiac Arrest Syndrome; Emergency Medical Services

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Non-traumatic OHCA (as confirmed in notes of ambulance crew) with ROSC obtained before transport to hospital
• Age > 18

Exclusion Criteria

• Traumatic cause of arrest (NB asphyxia due to hanging, electrocutions and drowning are not considered as traumatic arrests in this study, as normal ALS algorithms (special circumstances) are followed for these patients
• No ROSC before leaving OHCA
• Age <18
• Informed opt out of medical research of patient

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Medical Center Groningen

OTHER

Sponsor Role: lead

Responsible Party

Fabian Lucassen

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Ewoud ter Avest, dr

Role: PRINCIPAL_INVESTIGATOR

University Medical Center Groningen

Central Contacts

Fabian Lucassen, drs

Role: CONTACT

f.g.lucassen@umcg.nl

0031-503614359

Ewoud ter Avest, dr

Role: CONTACT

e.ter.avest@umcg.nl

0031-503614359

Other Identifiers

201900756

Identifier Type: -

Identifier Source: org_study_id