Bipolar 15 Charrières Office Resectoscope : Polypectomy Without Anesthesia

NCT ID: NCT04331652

Last Updated: 2023-03-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-12-14

Study Completion Date

2022-05-23

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aimed to the feasibility of polypectomy without anesthesia using a 15 Ch. resectoscope in women with uterine polyps.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Endometrial polyps are frequent gynecological pathologies leading to metrorrhagia, infertility, miscarriages and the risk of transformation into malignant pathology. The discovery of an endometrial polyp requires its removal.

The treatment of endometrial polyps is conventionally carried out by hysteroscopic resection under general anesthesia with a bipolar resector of 22 Charrières (Ch) or more after dilation of the uterine cervix in the operating room.

Following the recent appearance of a 15 Ch. bipolar mini-resectoscope, it seems that uterine dilation and anesthesia could be avoided by reducing the caliber of the instrument.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Polyps Uterus

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Polypectomy without anesthesia or analgo-sedation

Patient will undergo polypectomy without anesthesia.

Group Type EXPERIMENTAL

Polypectomy without anesthesia or analgo-sedation

Intervention Type PROCEDURE

Premedication: paracetamol 1g oral. Patient will undergo polypectomy without anesthesia. During the procedure, pain will be monitored using a pain assessment scale from 0 to 10 (0 meaning no pain and 10 meaning maximum pain imaginable). At any time, if the patient express a pain strictly superior to 4 an analgo-sedation will be proposed and/or general anesthesia.

Pulse and blood pressure will be monitored. Assessment of patient satisfaction after the intervention.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Polypectomy without anesthesia or analgo-sedation

Premedication: paracetamol 1g oral. Patient will undergo polypectomy without anesthesia. During the procedure, pain will be monitored using a pain assessment scale from 0 to 10 (0 meaning no pain and 10 meaning maximum pain imaginable). At any time, if the patient express a pain strictly superior to 4 an analgo-sedation will be proposed and/or general anesthesia.

Pulse and blood pressure will be monitored. Assessment of patient satisfaction after the intervention.

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Female patients aged 18 or over
* Patients with 1 to 2 endometrial polyps
* Polyps diagnosed by ultrasound and / or diagnostic hysteroscopy following a check-up for menometrorrhagia, infertility or during a check-up
* Polyps measuring less than 3 cm
* Have signed a consent form
* Be affiliated with a Health Insurance plan.

Exclusion Criteria

* Pregnant or lactating patient
* Cervical stenosis
* Patient having more than 2 polyps
* Polyps measuring 3 cm or more
* Malignant cells on histology
* Associated indication of endometrectomy or other endo-uterine gesture
* Hypersensitivity to remifentanil or to other fentanyl derivatives or to any of the excipients of the specialty used
* Hypersensitivity to propofol or to any of the excipients of the specialty used
* Cardiac pathology
* Diaphragmatic hernia
* Morbid obesity (BMI\> 35)
* Invasive cervical cancer
* Chronic obstructive pulmonary disease
* Patient presenting a strictly greater than 4 on a pain scale (from 0 to 10) during a diagnostic hysteroscopy
* Does not speak and / or understand French
* Be deprived of liberty or under guardianship.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Hopital Foch

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Angeline FAVRE-INHOFER, Dr

Role: PRINCIPAL_INVESTIGATOR

Hopital Foch

Marie Carbonnel, Dr

Role: STUDY_DIRECTOR

Hopital Foch

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hopital Foch

Suresnes, Île-de-France Region, France

Site Status

Countries

Review the countries where the study has at least one active or historical site.

France

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2019_0026

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

The Hysteroscopic Morcellator (HM).
NCT01537822 COMPLETED NA