Abnormal Pain Processing in COPD Patients

NCT ID: NCT04319523

Last Updated: 2020-03-24

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 65 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-11-01
• Study Completion Date: 2021-12-03

Brief Summary

Dyspnea, cough, and fatigue are the symptoms characteristic of moderate-severe COPD. Within the progression of disease was also reported a prevalence of 34-77% of pain symptoms in these patients. A review observed a higher score in pain intensity/interference associated with multiples pain locations of COPD patients. Pain in chronic diseases may appear to result from abnormalities in pain processing because of the damage and/or inflammation of peripheral structures.

Detailed Description

Dyspnea, cough, and fatigue are the symptoms characteristic of moderate-severe COPD. Within the progression of disease was also reported a prevalence of 34-77% of pain symptoms in these patients. A review observed a higher score in pain intensity/interference associated with multiples pain locations of COPD patients. Several studies reported that comorbidities, GOLD grade, and breathlessness may contribute to a higher pain prevalence in COPD patients because of the systemic inflammatory process and lung hyperinflation. Pain in chronic diseases may appear to result from abnormalities in pain processing and alteration of sensitization due to the damage and/or inflammation of peripheral structures.

Conditions

Pulmonary Disease, Chronic Obstructive; Pain

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

COPD patients

No interventions assigned to this group

Healthy subjects

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Between 50 and older age
• Accepted to sign the informed consent

Exclusion Criteria

• comorbidities with a course of chronic pain that interfered with evaluation
• the presence of cognitive impairment to understand the questionnaire

• Minimum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Universidad de Granada

OTHER

Sponsor Role: lead

Responsible Party

Marie Carmen Valenza

University of Granada

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Faculty of Health Sciences. University of Granada.

Granada, Andalusia, Spain

Countries

Spain

Other Identifiers

DF0087UG

Identifier Type: -

Identifier Source: org_study_id