Biomarkers of Chronic Obstructive Pulmonary Disease

NCT ID: NCT04963023

Last Updated: 2023-08-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

75 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-15

Study Completion Date

2023-07-01

Brief Summary

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There are few studies about immunological explorations in COPD. Because of the complications of lung biopsies, analyses are generally made on blood samples instead of lung tissue. No study tried to classify COPD vs Asthma vs ACOS. The investigators wondered if there were differences in biomarkers between these groups. The investigators decided to open a pilot-study among COPD patients followed in Amiens-University Hospital. Each patient will be examined and a blood-test will be performed.

Detailed Description

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Conditions

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COPD Asthma-COPD Overlap Syndrome Asthma

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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frequent exacerbation patients

Physical examinations

Intervention Type OTHER

BPCO physical examinations

blood test

Intervention Type DIAGNOSTIC_TEST

blood test in order to study immunologic markers

non frequent exacerbation patients

Physical examinations

Intervention Type OTHER

BPCO physical examinations

blood test

Intervention Type DIAGNOSTIC_TEST

blood test in order to study immunologic markers

Asthma-and-COPD overlap syndrome

Physical examinations

Intervention Type OTHER

BPCO physical examinations

blood test

Intervention Type DIAGNOSTIC_TEST

blood test in order to study immunologic markers

Asthmatic patients (without COPD)

Physical examinations

Intervention Type OTHER

BPCO physical examinations

blood test

Intervention Type DIAGNOSTIC_TEST

blood test in order to study immunologic markers

Interventions

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Physical examinations

BPCO physical examinations

Intervention Type OTHER

blood test

blood test in order to study immunologic markers

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* BPCO patients
* ACOS patients
* asthmatic patient without BPCO

Exclusion Criteria

* infection
* exacerbation
* immunosuppressive treatment
* immunosuppressive disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire, Amiens

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Amiens

Amiens, , France

Site Status

Countries

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France

Other Identifiers

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PI2021_843_0051

Identifier Type: -

Identifier Source: org_study_id

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