Hypercapnic Acute Respiratory Failure in the ICU : the YETI Study

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

862 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-12-14

Study Completion Date

2022-07-13

Brief Summary

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Hypercapnia is a frequent clinical situation defined as an elevation of the partial pressure of carbon dioxide (PaCO2) above 45 mmHg. Several physiopathological parameters such as respiratory minute volume, dead space volume or CO2 production influence the PaCO2. Therefore, hypercapnia can affect the time of various diseases.

Available epidemiological data regarding hypercapnia are from studies investigating the efficacy of non-invasive ventilation (NIV), with different population cohorts. However, their interpretation must be cautious given the heterogeneity in patient case-mix and results.

Then, whether hypercapnia is a common reason for intensive care unit (ICU) admission, epidemiological data is scarce and heterogeneous. The aim of this study is to investigate the epidemiological, clinical determinants and outcomes of patients admitted to ICU with hypercapnic respiratory failure.

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Detailed Description

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Conditions

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Intensive Care Unit Syndrome Hypercapnia Acute Respiratory Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Hypercapnic respiratory failure

Patients with hypercapnic respiratory failure will be followed without any additional intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients ≥18 years old presenting with at least of the following items :

1. respiratory rate ≥ 25/min,
2. paradoxical motion of the abdomen,
3. intercostal retraction AND
* a PaCO2 \> 45 cm H20 before ICU admission or within the 12 hours following ICU admission.