Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases
NCT ID: NCT04283903
Last Updated: 2023-05-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
25 participants
OBSERVATIONAL
2019-05-01
2025-05-01
Brief Summary
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This project aims to analyze for the first time the whole large scale proteome and metabolome of peri-implant crevicular fluid (PICF) with an integrated approach from implants with peri-implant diseases.
Twenty-five patients with at least one implant with peri-implant mucositis and one implant with peri-implantitis will be selected. For each of the selected participants, the PICF from an implant with peri-implant mucositis and from an implant with peri-implantitis will be sampled two different times before treatment. One year after the corresponding treatment is provided, the PICF of the treated implants with peri-implantitis will be sampled again.
Both proteomic and metabolomic profiling of the samples will be carried out. The most important strength of this project will be the ability to evaluate together the whole proteome and the whole metabolome and to integrate them in the same framework.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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PICF
PICF collection from 4 sites
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
ALL
No
Sponsors
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Universidad Complutense de Madrid
OTHER
Responsible Party
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Locations
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Department of Periodontology, University Complutense Madrid, Spain
Madrid, , Spain
Countries
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Central Contacts
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Facility Contacts
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Mariano Sanz Alonso
Role: primary
Other Identifiers
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Metabol_Proteom_Implants
Identifier Type: -
Identifier Source: org_study_id
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