A Study to Evaluate LY3154207 on the Brain of Healthy Participants

NCT ID: NCT04258826

Last Updated: 2022-02-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-15

Study Completion Date

2022-01-28

Brief Summary

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The purpose of this study is to learn more about how LY3154207 affects the brain of healthy participants by using magnetic resonance imaging. The study will last up to about nine weeks for each participant and may include up to four visits to the study center.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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LY3154207

LY3154207 administered orally in one of two study periods.

Group Type EXPERIMENTAL

LY3154207

Intervention Type DRUG

LY3154207 administered orally.

Placebo

Placebo administered orally in one of two study periods.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Placebo administered orally.

Interventions

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LY3154207

LY3154207 administered orally.

Intervention Type DRUG

Placebo

Placebo administered orally.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

-Overtly healthy males and non-childbearing females, as determined through medical history and physical examination

Exclusion Criteria

* Have known or ongoing psychiatric disorders
* Have contraindications to magnetic resonance imaging (MRI)
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Eli Lilly and Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)

Role: STUDY_DIRECTOR

Eli Lilly and Company

Locations

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Northwestern University

Chicago, Illinois, United States

Site Status

Countries

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United States

Other Identifiers

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I7S-MC-HBEM

Identifier Type: OTHER

Identifier Source: secondary_id

17294

Identifier Type: -

Identifier Source: org_study_id

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