Influence of Serum Sodium Levels on Bone Metabolism and Turnover in Hospitalized Patients
NCT ID: NCT04227301
Last Updated: 2025-05-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
52 participants
OBSERVATIONAL
2020-02-13
2025-02-24
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Hyponatremic patients
Patients hospitalized at the University Hospital of Basel and presenting with hyponatremia will be screened for the study
blood sampling
blood sampling for measurement of bone markers after a fasting period of at least 6 hours
Interventions
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blood sampling
blood sampling for measurement of bone markers after a fasting period of at least 6 hours
Eligibility Criteria
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Inclusion Criteria
* age 18 to 99-year-old
* Informed consent as documented by signature
Exclusion Criteria
* Hypertonic hyponatremia with serum osmolality \> 300 mOsm/kg
* End of life care (palliative treatment)
* End stage kidney disease (dialysis)
* Acute liver failure
* Wernicke encephalopathy
* Hepatic encephalopathy during last 2 months
* Hepato-renal syndrome
* Any bone disease requiring treatment in the last three years
* History of fragility fractures
* Pre-menopausal women
* Hypogonadism (diagnosed before hospitalization)
* Hyperthyroidism
* Steroid therapy
18 Years
99 Years
ALL
No
Sponsors
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University Hospital, Basel, Switzerland
OTHER
Responsible Party
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Principal Investigators
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Mirjam Christ-Crain, Prof. Dr. med
Role: PRINCIPAL_INVESTIGATOR
Endocrinology, Diabetology and Metabolism, University Hospital Basel
Locations
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Endocrinology, Diabetes and Metabolism, University Hospital Basel
Basel, , Switzerland
Countries
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Other Identifiers
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2019-01858; me18ChristCrain6
Identifier Type: -
Identifier Source: org_study_id
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