Safe Options for ACL Recovery

NCT ID: NCT04225468

Last Updated: 2022-11-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-12

Study Completion Date

2022-06-03

Brief Summary

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The purpose of the proposed work is to test a brief opioid exposure reduction program (ACL-OERP) designed to improve health literacy about opioid use following surgeries. This intervention is specifically designed to be used with patients (or for patients under 18, the patient and caregiver) undergoing Anterior Cruciate Ligament (ACL) reconstruction, a painful surgery that is often followed by at least 7 days of opioid medication.

Detailed Description

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The goal of this study is to test whether the ACL-OERP intervention (vs. a treatment as usual \[TAU\] comparison) improves knowledge of (1) risks associated with opioid self-administration (development of tolerance, dangers of concomitant sedative use, taking as prescribed for safety), (2) expected pain following ACL reconstruction, (3) accurate pain assessment, (4) and weaning from opioid to non-narcotic analgesics.

There will be one control arm (TAU) and two intervention arms, both of which are experimental. Both will receive the ACL-OERP before surgery, and the second arm will also receive a "booster" intervention session of the intervention 3 days after surgery.

In addition, investigators wish to compare the amount of opioid self-administered in the intervention groups (vs. TAU comparison) to assess whether this knowledge reduces self-administration of opioid. The project will also examine whether the implementation of the booster intervention session in the third arm improves these outcomes compared to the other intervention arm.

Conditions

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Anterior Cruciate Ligament Injuries Opioid Use

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Treatment As Usual (TAU)

No intervention will be administered.

Group Type NO_INTERVENTION

No interventions assigned to this group

Opioid Exposure Reduction Program 1 (OERP1)

Participants will engage in a brief, educational intervention at their pre-surgery appointment approximately 2-3 weeks before ACL reconstruction surgery.

Group Type EXPERIMENTAL

ACL Opioid Exposure Reduction Program

Intervention Type BEHAVIORAL

Subjects will engage in a brief, educational which includes information about the appropriate use of opioid pain medication, exposure and tolerance, the definition of misuse and opioid-related harms, how to wean off medication, alternative pain management strategies, and appropriate disposal of leftover medication.

Opioid Exposure Reduction Program 2 (OERP2)

Participants will engage in the same intervention as OERP1, but those in OERP2 will also receive a 5-minute "booster" intervention session 3 days after surgery.

Group Type EXPERIMENTAL

ACL Opioid Exposure Reduction Program

Intervention Type BEHAVIORAL

Subjects will engage in a brief, educational which includes information about the appropriate use of opioid pain medication, exposure and tolerance, the definition of misuse and opioid-related harms, how to wean off medication, alternative pain management strategies, and appropriate disposal of leftover medication.

Interventions

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ACL Opioid Exposure Reduction Program

Subjects will engage in a brief, educational which includes information about the appropriate use of opioid pain medication, exposure and tolerance, the definition of misuse and opioid-related harms, how to wean off medication, alternative pain management strategies, and appropriate disposal of leftover medication.

Intervention Type BEHAVIORAL

Other Intervention Names

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ACL-OERP

Eligibility Criteria

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Inclusion Criteria

* Presenting for a pre-operatory appointment at the study site for ACL reconstruction with patellar tendon autograft surgery.
* Be able to return to the clinic at least one time within the first 10 days post-op.

Exclusion Criteria

* Under 12 years of age
* Contraindication to opioids
* Unable to understand intervention material in English
Minimum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Memphis

OTHER

Sponsor Role collaborator

Campbell Clinic

OTHER

Sponsor Role collaborator

Karen Derefinko, PhD

OTHER

Sponsor Role lead

Responsible Party

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Karen Derefinko, PhD

Assistant Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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University of Tennessee Health Science Center

Memphis, Tennessee, United States

Site Status

Countries

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United States

Related Links

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https://uthsc.edu

UTHSC main website

Other Identifiers

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19-07075-XP

Identifier Type: -

Identifier Source: org_study_id

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