The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Revision Knee Arthroplasty

NCT ID: NCT01191593

Last Updated: 2013-08-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2013-04-30

Brief Summary

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The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing pain and morphine consumption after revision knee arthroplasty.

Detailed Description

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Conditions

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Postoperative Pain Knee Arthroplasty

Keywords

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Adductor-Canal-Blockade postoperative pain US-guided nerve block revision knee arthroplasty

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Adductor-Canal-Blockade with ropivacaine

Group Type EXPERIMENTAL

Adductor-Canal-Blockade with Ropivacaine

Intervention Type PROCEDURE

US-guided Adductor-Canal-Blockade with ropivacaine 7,5 mg/ml

Adductor-Canal-blockade with saline

Group Type PLACEBO_COMPARATOR

Adductor-Canal-blockade with saline

Intervention Type PROCEDURE

US-guided Adductor-Canal-blockade with saline

Interventions

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Adductor-Canal-Blockade with Ropivacaine

US-guided Adductor-Canal-Blockade with ropivacaine 7,5 mg/ml

Intervention Type PROCEDURE

Adductor-Canal-blockade with saline

US-guided Adductor-Canal-blockade with saline

Intervention Type PROCEDURE

Other Intervention Names

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Naropine Postoperative pain US-guided nerve block Placebo block

Eligibility Criteria

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Inclusion Criteria

* Revision Knee Arthroplasty in general anaesthesia
* American society of anesthesiologists (ASA) 1-3
* BMI 18-40
* Written informed consent

Exclusion Criteria

* Can not cooperate to the exam
* Do not speak or understand Danish
* Drug allergy
* Alcohol or drug abuse
Minimum Eligible Age

40 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Pia Jaeger

M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Pia Jæger, MD

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Locations

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Department of Anaesthesia and Surgery, HOC, Rigshospitalet, Denmark

Copenhagen, København Ø, Denmark

Site Status

Countries

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Denmark

References

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Jaeger P, Koscielniak-Nielsen ZJ, Schroder HM, Mathiesen O, Henningsen MH, Lund J, Jenstrup MT, Dahl JB. Adductor canal block for postoperative pain treatment after revision knee arthroplasty: a blinded, randomized, placebo-controlled study. PLoS One. 2014 Nov 11;9(11):e111951. doi: 10.1371/journal.pone.0111951. eCollection 2014.

Reference Type DERIVED
PMID: 25386752 (View on PubMed)

Other Identifiers

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2010-021161-71

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

SM1-PJ-10

Identifier Type: -

Identifier Source: org_study_id