Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity
NCT ID: NCT04225247
Last Updated: 2020-01-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
105 participants
INTERVENTIONAL
2018-03-07
2018-10-07
Brief Summary
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A total of 105 patients with dentin hypersensitivity are randomized into three groups. Scaling and root debridement are performed for all the groups. This study compares two seventh generation bonding agents and taking fluoride varnish as control group.
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Detailed Description
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After diagnosis of dentin hypersensitivity, the patients signed a consent form stating their voluntary participation in the research. The discomfort internal scale score and Schiff cold air sensitivity scale scores are recorded at baseline, immediately after the intervention, after 01 week and after 01 month. Discomfort internal scale score are recorded for every participant using dental explorer in the mesial and distal direction on the exposed surface of the affected teeth for tactile stimulation. For schiff cold air sensitivity scale scores an air syringe system was used to check the evaporative response on the affected teeth of the participants and the scores are recorded.
All the patients received scaling and root debridement as a standard protocol treatment. Dentin bonding agents and fluoride varnish are applied to the participants. All the participants are instructed to fast for two hours after the treatment. All the records are made on subjective response of patients.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Group-I Single Bond Universal
it is a seventh generation bonding agent used as desensitizer, manufactured by 3M ESPE.
applied on the affected surface of the group-I participants.
Single Bond Universal
Single bond universal (by 3M ESPE) is a seventh generation bonding agents used as desensitizers in the present study.
Group-II Xeno V+
it is a seventh generation bonding agent used as desensitizer, manufactured by Dentsply.
applied on the affected surface of the group-II participants.
Xeno V+
Xeno V+ (by Dentsply) is a seventh generation bonding agents used as desensitizers in the present study.
Group-III Bifluorid 12
it is a fluoride varnish used as desensitizer, manufactured by VOCO. applied on the affected surface of the group-III participants.
Bifluorid 12
it is a fluoride varnish by VOCO.
Interventions
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Single Bond Universal
Single bond universal (by 3M ESPE) is a seventh generation bonding agents used as desensitizers in the present study.
Bifluorid 12
it is a fluoride varnish by VOCO.
Xeno V+
Xeno V+ (by Dentsply) is a seventh generation bonding agents used as desensitizers in the present study.
Eligibility Criteria
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Inclusion Criteria
* Hypersensitive teeth to air and tactile stimultaion
* Gingival recession of Miller Class I and II
* Score 1 of Silness and Loe Plaque index
* Participants who have no sysytemic illness
* Patients who agree to give consent were included in the study.
Exclusion Criteria
* Fractured restoration or cracked teeth
* Teeth undergoing orthodontic or periodontal treatment at sensitive site
* Patients who had dental bleaching in last 03 months
* Patients taking pain killers
* Smokers
* Pregnant and nursing females were excluded from the study
18 Years
45 Years
ALL
Yes
Sponsors
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Dow University of Health Sciences
OTHER
Responsible Party
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Sumaiya Shabbir
Principal Investigator
Locations
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Dow University of health Sciences
Karachi, Sindh, Pakistan
Countries
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References
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Yu X, Liang B, Jin X, Fu B, Hannig M. Comparative in vivo study on the desensitizing efficacy of dentin desensitizers and one-bottle self-etching adhesives. Oper Dent. 2010 May-Jun;35(3):279-86. doi: 10.2341/09-346-C.
Ferrari M, Cagidiaco MC, Kugel G, Davidson CL. Clinical evaluation of a one-bottle bonding system for desensitizing exposed roots. Am J Dent. 1999 Oct;12(5):243-9.
Torres CR, Silva TM, Fonseca BM, Sales AL, Holleben P, Di Nicolo R, Borges AB. The effect of three desensitizing agents on dentin hypersensitivity: a randomized, split-mouth clinical trial. Oper Dent. 2014 Sep-Oct;39(5):E186-94. doi: 10.2341/13-057. Epub 2014 Apr 10.
Hajizadeh H, Nemati-Karimooy A, Majidinia S, Moeintaghavi A, Ghavamnasiri M. Comparing the effect of a desensitizing material and a self-etch adhesive on dentin sensitivity after periodontal surgery: a randomized clinical trial. Restor Dent Endod. 2017 Aug;42(3):168-175. doi: 10.5395/rde.2017.42.3.168. Epub 2017 Jul 21.
Panduric V, Knezevic A, Tarle Z, Sutalo J. The efficiency of dentine adhesives in treating non-caries cervical lesions. J Oral Rehabil. 2001 Dec;28(12):1168-74. doi: 10.1046/j.1365-2842.2001.00779.x.
Bartold PM. Dentinal hypersensitivity: a review. Aust Dent J. 2006 Sep;51(3):212-8; quiz 276.
Polderman RN, Frencken JE. Comparison between effectiveness of a low-viscosity glass ionomer and a resin-based glutaraldehyde containing primer in treating dentine hypersensitivity--a 25.2-month evaluation. J Dent. 2007 Feb;35(2):144-9. doi: 10.1016/j.jdent.2006.06.005. Epub 2006 Sep 14.
Schiff T, Dotson M, Cohen S, De Vizio W, McCool J, Volpe A. Efficacy of a dentifrice containing potassium nitrate, soluble pyrophosphate, PVM/MA copolymer, and sodium fluoride on dentinal hypersensitivity: a twelve-week clinical study. J Clin Dent. 1994;5 Spec No:87-92.
Shabbir S, Ahmed S, Zaidi SJA, Riaz S, Sarwar H, Taqi M, Rahman Khan ZU. Efficacy of seventh generation bonding agents as desensitizers in patients with dentin hypersensitivity: a randomized clinical trial. BMC Oral Health. 2024 May 14;24(1):562. doi: 10.1186/s12903-024-04352-0.
Other Identifiers
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2358847
Identifier Type: -
Identifier Source: org_study_id
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