The Effect of Regional Anaesthesia and Genetic Factors in the Development of Chronic Pain Following Total Knee Arthroplasty
NCT ID: NCT04206046
Last Updated: 2022-10-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
200 participants
INTERVENTIONAL
2017-06-01
2023-12-30
Brief Summary
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It will also focus on genetic factors and their influence on chronic pain.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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General Anaesthesia
Patients will receive a general anaesthetic, together with a femoral nerve block.
General anaesthesia
patients will receive a general anaesthetic and a femoral nerve block
Spinal Anaesthesia
Patients will receive a spinal anaesthetic
Spinal anaesthesia
Patients will receive a spinal anaesthetic
Interventions
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Spinal anaesthesia
Patients will receive a spinal anaesthetic
General anaesthesia
patients will receive a general anaesthetic and a femoral nerve block
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* known case of chronic pain syndromes
* arthroplasty not due to osteoarthritis
* sensitivity to any drugs used in protocol
18 Years
75 Years
ALL
No
Sponsors
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Sciberras, Stephen M.D.
INDIV
Responsible Party
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Stephen Sciberras
Lead investigator
Locations
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Mater Dei Hospital
Msida, , Malta
Countries
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References
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Sciberras SC, Vella AP, Vella B, Spiteri J, Mizzi C, Borg-Xuereb K, LaFerla G, Grech G, Sammut F. A randomized, controlled trial on the effect of anesthesia on chronic pain after total knee arthroplasty. Pain Manag. 2022 Sep;12(6):711-723. doi: 10.2217/pmt-2021-0081. Epub 2022 Mar 30.
Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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001
Identifier Type: -
Identifier Source: org_study_id
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