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FTO Gene Variants and Diet in Obesity

NCT ID: NCT04205318

Last Updated: 2019-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-03-01

Study Completion Date

2018-12-31

Brief Summary

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Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are associated with obesity and to assess whether these associations were modified by lifestyle factors. The study included 200 obese and 200 non-obese individuals from Turkey. Our study suggests that the effect of the SNPs on obesity traits is likely to be influenced by lifestyle factors in this Turkish population.

Detailed Description

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Conditions

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Obesity Diet Habit Genetic Predisposition

Keywords

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obesity gene-diet interaction FTO gene variant

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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study

obese (BMI ≥25.00 kg/m2, n=200)

No interventions assigned to this group

control

non-obese (BMI= 18.50-24.99 kg/m2, n=200)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. attending routine outpatient visits,
2. aged 24 to 50 years,
3. having a BMI ≥ 18.50 kg/m2
Minimum Eligible Age

24 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Reading

OTHER

Sponsor Role collaborator

The Scientific and Technological Research Council of Turkey

OTHER

Sponsor Role collaborator

Hacettepe University

OTHER

Sponsor Role lead

Responsible Party

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ZEHRA BUYUKTUNCER

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Zehra Buyuktuncer

Role: PRINCIPAL_INVESTIGATOR

Hacettepe University, Department of Nutrition and Dietetics, Ankara, TURKEY

Vimales Karani Santhanakrishnan

Role: PRINCIPAL_INVESTIGATOR

Department of Food and Nutritional Sciences, University of Reading, UK

Locations

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Zehra Buyuktuncer

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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GO15/612-11

Identifier Type: -

Identifier Source: org_study_id