Tongue Depressor-related Ischemia-Reperfusion Injury in Tongue

NCT ID: NCT04205253

Last Updated: 2019-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

64 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-01

Study Completion Date

2019-04-01

Brief Summary

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This study aimed to detect tongue edema associated with the pressure exerted by a rigid direct laryngoscope by measuring the tongue area using USG in patients undergoing suspension laryngoscopy (SL) procedures.

Detailed Description

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Suspension laryngoscopy (SL) is a surgical procedure for both diagnostic and therapeutic purposes. In this procedure, a rigid direct laryngoscope is inserted orally, and the tongue and the base of the tongue are compressed.The tongue is an ideal organ for evaluation with ultrasonography. This study aimed to detect the occurrence of tongue edema through ultrasonography examination due to the rigid direct laryngoscope in SL procedures.

Conditions

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Side Effect Ischemia Reperfusion Injury Edema Tongue Enlarged

Keywords

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tongue ischemia-reperfusion injury side effect edema suspension laryngoscopy

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Study

The first group is the study group. Patients aged 20 years or older and were to undergo suspension laryngoscopy procedure were eligible for inclusion in this group. Tongue areas were measured twice by submental USG. The first measurements (TA1) were done immediately after endotracheal intubation before introducing the rigid direct laryngoscope, whereas the second measurements (TA2) were done after the SL procedure and after removing the rigid direct laryngoscope just before extubation.The difference between TA2 and TA1 (i.e., TA2-TA1) were used to define the occurrence of tongue edema as study group.

Ultrasonography imaging

Intervention Type DIAGNOSTIC_TEST

This study aimed to evaluate the tongue areas and compare the tongue areas before the implementation of rigid direct laryngoscope and after the rigid direct laryngoscope.

Control

The second group was the control group, which included patients who did not need SL and any head and neck procedures.The tongue areas of these patients were measured twice by submental USG as in the study group. The TA1 measurements were done immediately after endotracheal intubation, whereas the TA2 measurements were done at the end of the surgical procedure just before extubation. The difference between TA2 and TA1 (i.e., TA2-TA1) were used to define the occurrence of tongue edema as study group.

Ultrasonography imaging

Intervention Type DIAGNOSTIC_TEST

This study aimed to evaluate the tongue areas and compare the tongue areas before the implementation of rigid direct laryngoscope and after the rigid direct laryngoscope.

Interventions

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Ultrasonography imaging

This study aimed to evaluate the tongue areas and compare the tongue areas before the implementation of rigid direct laryngoscope and after the rigid direct laryngoscope.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients aged 20 years or older
* Patients who undergo suspension laryngoscope procedure


Patients aged 20 years or older Patients who did not need suspension laryngoscopy and any head and neck procedures

Exclusion Criteria

* refusal to participate
* age of \<20 years
* history of syndromal craniofacial abnormalities
* occurrence of tongue masses
* history of craniofacial surgery
* history of burns, trauma or radiotherapy involving the head and neck region
* neurologic disorders and patients with obstructive sleep apnea syndrome (OSAS)
* active inflammation in the head and neck region
* cervical rigidity limiting neck flexion and head extension

Control group
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Selcuk University

OTHER

Sponsor Role lead

Responsible Party

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Ozkan Onal

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ozkan Onal, Professor

Role: PRINCIPAL_INVESTIGATOR

Selcuk University

Locations

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Selcen Celik

Konya, Selcuklu, Turkey (Türkiye)

Site Status

Selcuk University

Konya, Selcuklu, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Onal M, Colpan B, Elsurer C, Bozkurt MK, Onal O, Turan A. Is it possible that direct rigid laryngoscope-related ischemia-reperfusion injury occurs in the tongue during suspension laryngoscopy as detected by ultrasonography: a prospective controlled study. Acta Otolaryngol. 2020 Jul;140(7):583-588. doi: 10.1080/00016489.2020.1743353. Epub 2020 Mar 30.

Reference Type DERIVED
PMID: 32223688 (View on PubMed)

Other Identifiers

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2018/330

Identifier Type: -

Identifier Source: org_study_id