Topcon DRI OCT Triton With SS-OCT Angio Software Evaluation Study

NCT ID: NCT04201340

Last Updated: 2022-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

211 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-12-11

Study Completion Date

2022-10-20

Brief Summary

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Comparisons for vascular structure visualization in the retina and choroid.

Detailed Description

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Conditions

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Fluorescein Angiography Imaging

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Subjects Presenting with Normal Eyes

Subjects with no known ocular diseases will be imaged on the DRI OCT Triton with SS-OCT Angio software, Zeiss Cirrus HD-OCT 5000, and TRC-50DX

DRI OCT Triton with SS-OCT Angio software

Intervention Type DEVICE

The Topcon DRI OCT Triton with SS-OCT Angio software is an OCT with a fundus camera used for diagnostic purposes

Cirrus HD-OCT 5000

Intervention Type DEVICE

The Zeiss Cirrus HD-OCT 5000 is an OCT used for diagnostic purposes

TRC-50DX

Intervention Type DEVICE

The TRC-50DX retinal camera images the fundus used for diagnostic purposes

Subjects with retinal pathology present in the vasculature

Subjects with retinal pathology likely to present in the vasculature will be imaged on the DRI OCT Triton with SS-OCT Angio software, Zeiss Cirrus HD-OCT 5000, and TRC-50DX

DRI OCT Triton with SS-OCT Angio software

Intervention Type DEVICE

The Topcon DRI OCT Triton with SS-OCT Angio software is an OCT with a fundus camera used for diagnostic purposes

Cirrus HD-OCT 5000

Intervention Type DEVICE

The Zeiss Cirrus HD-OCT 5000 is an OCT used for diagnostic purposes

TRC-50DX

Intervention Type DEVICE

The TRC-50DX retinal camera images the fundus used for diagnostic purposes

Interventions

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DRI OCT Triton with SS-OCT Angio software

The Topcon DRI OCT Triton with SS-OCT Angio software is an OCT with a fundus camera used for diagnostic purposes

Intervention Type DEVICE

Cirrus HD-OCT 5000

The Zeiss Cirrus HD-OCT 5000 is an OCT used for diagnostic purposes

Intervention Type DEVICE

TRC-50DX

The TRC-50DX retinal camera images the fundus used for diagnostic purposes

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Subjects 22 years of age or older on the date of informed consent
2. Subjects able to understand the written informed consent and willing to participate as evidenced by signing the informed consent
3. Subjects who have not participated in the DRI OCT Triton with SS OCT Angio software Evaluation Prestudy
4. Subjects with normal eye exam bilaterally (laser refractive surgery and cataracts are acceptable)
5. IOP ≤ 21 mmHg bilaterally
6. BCVA 20/40 or better bilaterally


1. Subjects 22 years of age or older on the date of informed consent
2. Subjects able to understand the written informed consent and willing to participate as evidenced by signing the informed consent
3. Subjects who have not participated in the DRI OCT Triton with SS OCT Angio software Evaluation Prestudy
4. BCVA 20/400 or better in the study eye
5. Diagnosis of some type of retinal pathology likely to present in the vasculature in at least one eye as determined by the investigator, may include, but is not limited to: Diabetic retinopathy, Retinal Vein occlusions, Exudative AMD or Macular telangiectasia with expected presentation in the vasculature of, including but not limited to, microaneurysms, capillary dropout and/or choroidal neovascularization.

Exclusion Criteria

1. Subjects unable to tolerate ophthalmic imaging
2. Subjects with ocular media not sufficiently clear to obtain acceptable OCT-A scans
3. Subjects with known allergy to fluorescein, or subjects having liver disease, or end-stage renal disease
4. Narrow angle
5. History of leukemia, dementia or multiple sclerosis
6. Concomitant use of hydroxychloroquine or chloroquine
7. Subjects where the study eye was treated after screening and before imaging


1. Subjects unable to tolerate ophthalmic imaging
2. Subjects with ocular media not sufficiently clear to obtain acceptable OCT-A scans
3. Subjects with known allergy to fluorescein or if ICGA is clinically indicated, indocyanine green dyes, shellfish, iodine, or subjects having liver disease, or end-stage renal disease
4. History of leukemia, dementia or multiple sclerosis
5. Concomitant use of hydroxychloroquine or chloroquine
6. Subjects where the study eye was treated after screening and before imaging
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Topcon Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mayra Tafreshi

Role: STUDY_DIRECTOR

Topcon Corporation

Locations

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Southeast Retina Center

Augusta, Georgia, United States

Site Status

Countries

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United States

Other Identifiers

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Triton OCT-A

Identifier Type: -

Identifier Source: org_study_id

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