OCT Angiography Software Evaluation Study

NCT ID: NCT04701931

Last Updated: 2023-07-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

135 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-07

Study Completion Date

2023-06-06

Brief Summary

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Comparisons for vascular structure visualization in the retina and choroid.

Detailed Description

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Evaluate the clinical performance of the Maestro2 OCTA for the visualization of the vascular structures of the retina and choroid.

Conditions

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Retina Condition Followed by Fluorescein Angiography Imaging

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Subjects presenting with Normal Eyes

Subjects with no known ocular diseases will be imaged on the Maestro2 OCT, Zeiss Cirrus HD-OCT 5000, and TRC-50DX

Maestro2 OCTA

Intervention Type DEVICE

The Maestro2 OCTA with SS-OCT Angio software is an OCT with a fundus camera used for diagnostic purposes

Cirrus HD-OCT 5000

Intervention Type DEVICE

The Zeiss Cirrus HD-OCT 5000 is an OCT used for diagnostic purposes

TRC-50DX

Intervention Type DEVICE

The TRC-50DX retinal camera images the fundus used for diagnostic purposes

Subjects with retinal pathology present in the eye

Subjects with no known ocular diseases will be imaged on the Maestro2 OCT, Zeiss Cirrus HD-OCT 5000, and TRC-50DX

Maestro2 OCTA

Intervention Type DEVICE

The Maestro2 OCTA with SS-OCT Angio software is an OCT with a fundus camera used for diagnostic purposes

Cirrus HD-OCT 5000

Intervention Type DEVICE

The Zeiss Cirrus HD-OCT 5000 is an OCT used for diagnostic purposes

TRC-50DX

Intervention Type DEVICE

The TRC-50DX retinal camera images the fundus used for diagnostic purposes

Interventions

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Maestro2 OCTA

The Maestro2 OCTA with SS-OCT Angio software is an OCT with a fundus camera used for diagnostic purposes

Intervention Type DEVICE

Cirrus HD-OCT 5000

The Zeiss Cirrus HD-OCT 5000 is an OCT used for diagnostic purposes

Intervention Type DEVICE

TRC-50DX

The TRC-50DX retinal camera images the fundus used for diagnostic purposes

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. 22 years of age or older on the date of informed consent
2. Able to understand the written informed consent and willing to participate by signing the informed consent
3. Current diagnosis of one or more of the following pathologies in the study eye in two subgroups:

1. Vascular pathologies primarily visualized in Superficial and Deep en face OCTA slabs, including but not limited to Diabetic Retinopathy (DR), Branch Retinal Vein Occlusion (BRVO), Central Retinal Vein Occlusion (CRVO), Central Retinal Arterial Occlusion (CRAO), Macular Telangiectasia (MacTel), Sickle Cell Retinopathy (SCR)

1. 22 years of age or older on the date of informed consent
2. Able to understand the written informed consent and willing to participate by signing the informed consent

Exclusion Criteria

1\. Subjects previously enrolled in Maestro2 OCTA feasibility study 2. Subjects who are pregnant or lactating\* 3. Unable to complete the required clinical examinations 4. Contraindication to pupil dilation 6. Known allergy or other contradictions to fluorescein and/or to indocyanine green or iodides


1\. Subjects previously enrolled in Maestro2 OCTA feasibility study 2. Subjects who are pregnant or lactating\* 3. Unable to complete the required clinical examinations 4. Clinically significant findings in the study eye in clinical examination 5. Contraindication to pupil dilation 7. Known allergy or contradictions to fluorescein and/or to indocyanine green or iodides
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Topcon Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mayra Tafreshi

Role: STUDY_DIRECTOR

CPAD

Locations

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Orange County Retina Medical Group

Santa Ana, California, United States

Site Status

Southeast Retina Center

Augusta, Georgia, United States

Site Status

Countries

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United States

Other Identifiers

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THS-TPCN-2020-003

Identifier Type: -

Identifier Source: org_study_id

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