Physical Activity Stress and Sleep in Adolescents

NCT ID: NCT04187885

Last Updated: 2019-12-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

56 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-09-03

Study Completion Date

2022-03-03

Brief Summary

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Adolescence is characterized by major transitions in sleep and circadian rhythm. This rapid pivotal period increases the risks of sleep debt and poor sleep quality, leading to pronounced diurnal fatigue and drowsiness. On the other hand, academic stress has been also associated with increased sleep disturbances.

Both academic stress and poor sleep in adolescents has been linked to increased sleepiness rate, reduced alertness, lower academic performances and the impairment of the control of energy balance through hyperphagia.

Despite the importance of sleep in holistic development, physical (i.e. recovery, metabolism, muscle growth, weight control), cognitive (i.e. learning, memory, decision-making, Vigilance). Few studies have been designed to improve this behavior among college adolescents, especially in times of academic stress.

Physical activity has been suggested as a non-pharmacological alternative treatment for sleep disorders . Generally, it is well established that the duration and quality of sleep were improved by regular physical activity among adolescents and far better, it was suggested that the exercise-mediated effect on sleep could be even observed in the short term. Moreover, it was suggested that aerobic exercise has positive effects on psychological stress and well-being of adolescents .

Therefore, APADOSLEEP trial, was designed to examine the effect of physical activity program on sleep during and outside periods of academic stress.

Detailed Description

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Counterbalanced, cross-over, pre-post trial where each subject acts as his own control.

Four sessions will be performed for each adolescent. Each session will be conducted over 5 days (from Monday to Friday):

Adolescents will take part randomly in four sessions. Physical activity program will be identical between sessions and groups. 60 minn of moderate to vigorous leisure activities and exercises will be proposed each day. Heart rate monitor will be used to control intensity of exercise during the physical activity program.

* Control session (CTL) outside academic stress period (represented by exams) and without the physical activity program.
* A session outside academic stress period, with the physical activity program (PAP).
* A session during an academic stress period without the physical activity program (AS).
* A session during an academic stress period with the physical activity program (ASPAP).

At each session:

* Continuous sleep assessments (duration and quality) by accelerometry
* Continuous physical activity and sedentary behaviour assessments by accelerometry
* one evaluation of melatonin peak from salivary specimens
* one evaluation of cortisol peak from salivary specimens
* An evaluation of the ad libitum food intake of the 5th day will be carried out by the weighing method.
* one assessment of cognitive performance
* An evaluation of subjective appetite sensations (hunger, fullness, desire to eat) of the 5th day
* An evaluation of subjective diurnal sleepiness (Karolinska) of the 5th day

Conditions

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Adolescent Problem Behavior

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Group/Cohort 1 : CTL

Label : control

Type : comparator

Description: Outside academic stress period (represented by exams), without the physical activity program (no Intervention).

Group Type ACTIVE_COMPARATOR

Group/Cohort 2: PAP

Intervention Type BEHAVIORAL

Each experimental session will be carried out over 5 days of a week. Adolescents will take part randomly in four sessions.

Physical activity program will be identical between sessions and groups. 60 min of moderate to vigorous leisure activities and exercises will be proposed each day. Heart rate monitor will be used to control intensity of exercise during the physical activity program.

Group/Cohort 2: PAP

Label : physical activity program without stress Type : experimental

Description: outside academic stress period (exams), with the physical activity program:60 min of mederate to vigorous leisure activities and exercises will be proposed from Monday to Thursday.

Group Type EXPERIMENTAL

Group/Cohort 2: PAP

Intervention Type BEHAVIORAL

Each experimental session will be carried out over 5 days of a week. Adolescents will take part randomly in four sessions.

Physical activity program will be identical between sessions and groups. 60 min of moderate to vigorous leisure activities and exercises will be proposed each day. Heart rate monitor will be used to control intensity of exercise during the physical activity program.

Group/Cohort 3: AS

Label : academic stress Type : experimental

Description: during academic stress period (exams), without the physical activity program (no Intervention)

Group Type EXPERIMENTAL

Group/Cohort 2: PAP

Intervention Type BEHAVIORAL

Each experimental session will be carried out over 5 days of a week. Adolescents will take part randomly in four sessions.

Physical activity program will be identical between sessions and groups. 60 min of moderate to vigorous leisure activities and exercises will be proposed each day. Heart rate monitor will be used to control intensity of exercise during the physical activity program.

Group/Cohort 4: ASPAP

Label : academic stress and physical activity program Type : experimental Description: during academic stress period (exams), with the physical activity program: 60 min of mederate to vigorous leisure activities and exercises will be proposed from Monday to Thursday.

Group Type EXPERIMENTAL

Group/Cohort 2: PAP

Intervention Type BEHAVIORAL

Each experimental session will be carried out over 5 days of a week. Adolescents will take part randomly in four sessions.

Physical activity program will be identical between sessions and groups. 60 min of moderate to vigorous leisure activities and exercises will be proposed each day. Heart rate monitor will be used to control intensity of exercise during the physical activity program.

Interventions

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Group/Cohort 2: PAP

Each experimental session will be carried out over 5 days of a week. Adolescents will take part randomly in four sessions.

Physical activity program will be identical between sessions and groups. 60 min of moderate to vigorous leisure activities and exercises will be proposed each day. Heart rate monitor will be used to control intensity of exercise during the physical activity program.

Intervention Type BEHAVIORAL

Other Intervention Names

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Physial activity Program

Eligibility Criteria

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Inclusion Criteria

* college adolescent Tanner stages 3-5

Exclusion Criteria

* Disorders and / or pathology of sleep
* Medical or surgical history not compatible with the study, any other chronic illness or injury that may interfere with the subject's abilities
* Take medication that may interfere with the results of the study (corticosteroids ...) or sleeping pills
* Surgical intervention in the previous 3 months
* Regular consumption of tobacco, cannabis or alcohol
* Special diet
Minimum Eligible Age

14 Years

Maximum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Biochimie Clinique LR99ES11

UNKNOWN

Sponsor Role collaborator

Department of Biochemistry, La Rabta Hospital, Tunisia.

UNKNOWN

Sponsor Role collaborator

Université de Toulon

OTHER

Sponsor Role collaborator

Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Amani Kallel, PHD

Role: PRINCIPAL_INVESTIGATOR

Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose

Central Contacts

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Amani Kallel, PHD, HDR

Role: CONTACT

0021696872787

Moncef Feki

Role: CONTACT

References

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Arora, T., and Grey, I. (2019). Sleep, obesity and cardiometabolic disease in children and adolescents. In Sleep and Health, (Elsevier), pp. 421-433.

Reference Type BACKGROUND

Colrain IM, Baker FC. Changes in sleep as a function of adolescent development. Neuropsychol Rev. 2011 Mar;21(1):5-21. doi: 10.1007/s11065-010-9155-5. Epub 2011 Jan 12.

Reference Type BACKGROUND
PMID: 21225346 (View on PubMed)

Dewald JF, Meijer AM, Oort FJ, Kerkhof GA, Bogels SM. The influence of sleep quality, sleep duration and sleepiness on school performance in children and adolescents: A meta-analytic review. Sleep Med Rev. 2010 Jun;14(3):179-89. doi: 10.1016/j.smrv.2009.10.004. Epub 2010 Jan 21.

Reference Type BACKGROUND
PMID: 20093054 (View on PubMed)

Haugland S, Wold B, Torsheim T. Relieving the pressure? The role of physical activity in the relationship between school-related stress and adolescent health complaints. Res Q Exerc Sport. 2003 Jun;74(2):127-35. doi: 10.1080/02701367.2003.10609074.

Reference Type BACKGROUND
PMID: 12848225 (View on PubMed)

Ivanenko A, Crabtree VM, Gozal D. Sleep and depression in children and adolescents. Sleep Med Rev. 2005 Apr;9(2):115-29. doi: 10.1016/j.smrv.2004.09.006.

Reference Type BACKGROUND
PMID: 15737790 (View on PubMed)

Kredlow MA, Capozzoli MC, Hearon BA, Calkins AW, Otto MW. The effects of physical activity on sleep: a meta-analytic review. J Behav Med. 2015 Jun;38(3):427-49. doi: 10.1007/s10865-015-9617-6. Epub 2015 Jan 18.

Reference Type BACKGROUND
PMID: 25596964 (View on PubMed)

Krietsch KN, Chardon ML, Beebe DW, Janicke DM. Sleep and weight-related factors in youth: A systematic review of recent studies. Sleep Med Rev. 2019 Aug;46:87-96. doi: 10.1016/j.smrv.2019.04.010. Epub 2019 Apr 23.

Reference Type BACKGROUND
PMID: 31100467 (View on PubMed)

Lang C, Brand S, Feldmeth AK, Holsboer-Trachsler E, Puhse U, Gerber M. Increased self-reported and objectively assessed physical activity predict sleep quality among adolescents. Physiol Behav. 2013 Aug 15;120:46-53. doi: 10.1016/j.physbeh.2013.07.001. Epub 2013 Jul 9.

Reference Type BACKGROUND
PMID: 23851332 (View on PubMed)

Lang C, Kalak N, Brand S, Holsboer-Trachsler E, Puhse U, Gerber M. The relationship between physical activity and sleep from mid adolescence to early adulthood. A systematic review of methodological approaches and meta-analysis. Sleep Med Rev. 2016 Aug;28:32-45. doi: 10.1016/j.smrv.2015.07.004. Epub 2015 Aug 5.

Reference Type BACKGROUND
PMID: 26447947 (View on PubMed)

Lund HG, Reider BD, Whiting AB, Prichard JR. Sleep patterns and predictors of disturbed sleep in a large population of college students. J Adolesc Health. 2010 Feb;46(2):124-32. doi: 10.1016/j.jadohealth.2009.06.016. Epub 2009 Aug 3.

Reference Type BACKGROUND
PMID: 20113918 (View on PubMed)

Norris R, Carroll D, Cochrane R. The effects of physical activity and exercise training on psychological stress and well-being in an adolescent population. J Psychosom Res. 1992 Jan;36(1):55-65. doi: 10.1016/0022-3999(92)90114-h.

Reference Type BACKGROUND
PMID: 1538350 (View on PubMed)

Stepanski EJ, Wyatt JK. Use of sleep hygiene in the treatment of insomnia. Sleep Med Rev. 2003 Jun;7(3):215-25. doi: 10.1053/smrv.2001.0246.

Reference Type BACKGROUND
PMID: 12927121 (View on PubMed)

Other Identifiers

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University Tunis El Manar

Identifier Type: -

Identifier Source: org_study_id

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