Added Value of N Acetyle Cysteine to Clomiphene Citrate in PCO

NCT ID: NCT04170439

Last Updated: 2021-04-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

108 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-11-20

Study Completion Date

2020-05-15

Brief Summary

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PCO is one of the factors associated with delayed conception

Detailed Description

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In an attempt to induce ovulation Clomiphene citrate can be given in conjunction with N acetyle cysteine

Conditions

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PCO

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Women who will receive clomiphe citrate plus N acetyle cysteine rally in arm number 1 And women who will receive clomiphene citrate and chromoum in arm number 22
Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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clomiphene plus metformin plus N acetyle cysteine

Women who will receive clomiphene citrate plus metformin plus n acetyle cysteine

Group Type OTHER

Clomiphene plus metformin plus N acetyle cysteine in arm number 1

Intervention Type DRUG

oral adminstration of clomiphene citrate plus metformin plus N acetyl cysteine or chromium

clomiphene plus metformin plus chromium

Women who will receive clomiphene plus metformin plus chromium

Group Type OTHER

Clomiphene citrate plus metformin with chromium

Intervention Type DRUG

oral adminstration of clomiphene citrate plus metformin and chromium

clomiphen citrate plus metformin

Women who will receive clomiphene plus metformin

Group Type OTHER

clomiphene citrate plus metformin

Intervention Type DRUG

oral adminstration of clomiphene citrate plus metformin

Interventions

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Clomiphene plus metformin plus N acetyle cysteine in arm number 1

oral adminstration of clomiphene citrate plus metformin plus N acetyl cysteine or chromium

Intervention Type DRUG

Clomiphene citrate plus metformin with chromium

oral adminstration of clomiphene citrate plus metformin and chromium

Intervention Type DRUG

clomiphene citrate plus metformin

oral adminstration of clomiphene citrate plus metformin

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* women with PCO

Exclusion Criteria

* women who donot have PCO
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role collaborator

Aljazeera Hospital

OTHER

Sponsor Role lead

Responsible Party

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Mahmoud Alalfy

Lecturer in national research crntre and Algezzera hospital ,egypt

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mahmoud Alalfy, PhD

Role: STUDY_DIRECTOR

Algezeera

Locations

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Algazeerah and Kasralainy hospital

Giza, , Egypt

Site Status

Algazeerah

Giza, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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chromium in infertility

Identifier Type: -

Identifier Source: org_study_id

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